Heterodyne holographic microscopy in total internal reflection is used for 3-D imaging of live cells labeled with 40nm gold particles, with shot-noise limited sensitivity. Fast acquisition times enable selective localization of tens of particles simultaneously.
© 2009 OSA
(090.0090) Holography : Holography
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.0180) Medical optics and biotechnology : Microscopy
(090.1995) Holography : Digital holography
N. Warnasooriya, F. Joud, P. Bun, S. Suck, M. Gross, M. Coppey-Moisan, and G. Tessier, "Heterodyne Holographic Microscopy for 3-D Imaging of Live Cells Labeled with Gold Nanoparticles," in Frontiers in Optics 2009/Laser Science XXV/Fall 2009 OSA Optics & Photonics Technical Digest, OSA Technical Digest (CD) (Optical Society of America, 2009), paper FThB4.
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