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Conferences > FiO > 2012 > FTh4C > FTh4C.1

Quantitative imaging and measurement of cell-substrate surface deformation by digital holography

Xiao Yu, Michael Cross, Changgeng Liu, David C. Clark, Donald T. Haynie, and Myung K. Kim

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Abstract

Quantitative phase microscopy by digital holography (DH-QPM) is introduced to study fibroblasts deforming collagen-coated polyacrylamide. Surface deformation has been quantitatively imaged and the traction force of fibroblasts has been measured from phase profiles by DH-QPM.

© 2012 Optical Society of America

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