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Conference Paper
Laser Applications to Chemical and Environmental Analysis
Annapolis, Maryland United States
February 9, 2004
ISBN: 1-55752-765-2
Bio-Optical II (TuC)

Multidimensional tissue imaging by matrix assisted laser desorption/ionization-ion mobility-mass spectrometry: advantages, challenges, and prospects for proteomics

John A. McLean, Stacy D. Sherrod, and David H. Russell

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Abstract

MALDI-imaging mass spectrometry correlates detailed analyte information with spatial distribution in biological tissue sections. By combining post-ionization ion mobility separation with mass analysis, difficult peak assignments arising from spectrum congestion are alleviated.

© 2004 Optical Society of America

OCIS Codes
(000.1430) General : Biology and medicine
(110.0110) Imaging systems : Imaging systems
(110.6880) Imaging systems : Three-dimensional image acquisition

Citation
J. A. McLean, S. D. Sherrod, and D. H. Russell, "Multidimensional tissue imaging by matrix assisted laser desorption/ionization-ion mobility-mass spectrometry: advantages, challenges, and prospects for proteomics," in Laser Applications to Chemical and Environmental Analysis, Technical Digest (Optical Society of America, 2004), paper TuC4.
http://www.opticsinfobase.org/abstract.cfm?URI=LACEA-2004-TuC4


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