MALDI-imaging mass spectrometry correlates detailed analyte information with spatial distribution in biological tissue sections. By combining post-ionization ion mobility separation with mass analysis, difficult peak assignments arising from spectrum congestion are alleviated.
© 2004 Optical Society of America
J. A. McLean, S. D. Sherrod, and D. H. Russell, "Multidimensional tissue imaging by matrix assisted laser desorption/ionization-ion mobility-mass spectrometry: advantages, challenges, and prospects for proteomics," in Laser Applications to Chemical and Environmental Analysis, Technical Digest (Optical Society of America, 2004), paper TuC4.
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