We have developed a rapid label-free protein biosensor based on null laser reflectance principles. Our imaging technique is capable of identifying and quantifying protein targets in <100pg/mL concentration while measuring >500 arrayed detection spots simultaneously.
© 2006 Optical Society of America
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.1470) Medical optics and biotechnology : Blood or tissue constituent monitoring
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
C. C. Striemer, C. R. Mace, and B. L. Miller, "Arrayed Imaging Reflectometry for Rapid Label-Free Clinical Diagnostics," in Frontiers in Optics, OSA Technical Digest (CD) (Optical Society of America, 2006), paper JWC3.
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