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Conference Paper
Laser Science
San Jose, California United States
October 11-15, 2009
ISBN: 978-1-55752-878-0
Single-Molecule Biophysics II (LSWD)

Photoactivatable Push-Pull Fluorophores for Single-Molecule Imaging in and out of Cells

Samuel J. Lord, Hsiao-lu D. Lee, Nicholas R. Conley, Marissa K. Lee, Michael A. Thompson, Reichel Samuel, Ryan Weber, Na Liu, Robert J. Twieg, and W. E. Moerner


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We have designed a series of photoactivatable push-pull organic fluorophores, single molecules of which can be imaged in living cells. Photoactivatable probes are needed for superresolution imaging schemes that require active control of single-molecule emission.

© 2009 APS

OCIS Codes
(100.0100) Image processing : Image processing
(100.6640) Image processing : Superresolution
(180.0180) Microscopy : Microscopy
(180.2520) Microscopy : Fluorescence microscopy

S. J. Lord, H. D. Lee, N. R. Conley, M. K. Lee, M. A. Thompson, R. Samuel, R. Weber, N. Liu, R. J. Twieg, and W. E. Moerner, "Photoactivatable Push-Pull Fluorophores for Single-Molecule Imaging in and out of Cells," in Frontiers in Optics 2009/Laser Science XXV/Fall 2009 OSA Optics & Photonics Technical Digest, OSA Technical Digest (CD) (Optical Society of America, 2009), paper LSWD2.

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