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Conference Paper
Optical Molecular Probes, Imaging and Drug Delivery
Monterey, California United States
April 4-6, 2011
ISBN: 978-1-55752-909-1
OMP Postdeadline Session (OTuD)

Two-photon Imaging of Intracellular Hydrogen Peroxide with a Chemoselective Fluorescence Probe

Hengchang Guo, Hossein Aleyasin, Scott Howard, Bryan C. Dickinson, Renee Haskew-Layton, Demirhan Kobat, Vivian Lin, David R. Rivera, Christopher J. Chang, Rajiv R. Ratan, and Chris Xu  »View Author Affiliations


http://dx.doi.org/10.1364/OMP.2011.OTuD3


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Abstract

We present two-photon molecular imaging of hydrogen peroxide production in mouse hippocampal neuronal cells using Peroxyfluor-6 acetoxymethyl ester, a highly sensitive, small-molecule probe for selective imaging of H2O2 within the living cells.

© 2011 OSA

OCIS Codes
(160.2540) Materials : Fluorescent and luminescent materials
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(180.4315) Microscopy : Nonlinear microscopy

Citation
H. Guo, H. Aleyasin, S. Howard, B. C. Dickinson, R. Haskew-Layton, D. Kobat, V. Lin, D. R. Rivera, C. J. Chang, R. R. Ratan, and C. Xu, "Two-photon Imaging of Intracellular Hydrogen Peroxide with a Chemoselective Fluorescence Probe," in Optics in the Life Sciences, OSA Technical Digest (CD) (Optical Society of America, 2011), paper OTuD3.
http://www.opticsinfobase.org/abstract.cfm?URI=OMP-2011-OTuD3


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