Nanoparticle Mediated Photothermal Therapy and Integrated miRNA Delivery

Kamilla Nørregaard; Ann-Katrine Vransø West; Poul Martin Bendix; Lene B. Oddershede

doi:10.1364/BODA.2013.JW3B.4

Optics in the Life Sciences
OSA Technical Digest (online) (Optica Publishing Group, 2013),
paper JW3B.4
•https://doi.org/10.1364/BODA.2013.JW3B.4

Nanoparticle Mediated Photothermal Therapy and Integrated miRNA Delivery

Kamilla Nørregaard, Ann-Katrine Vransø West, Poul Martin Bendix, and Lene B. Oddershede

Optical Trapping Applications 2013

Waikoloa Beach, Hawaii United States
14–18 April 2013
ISBN: 978-1-55752-966-4

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K. Nørregaard, A. V. West, P. M. Bendix, and L. B. Oddershede, "Nanoparticle Mediated Photothermal Therapy and Integrated miRNA Delivery," in Optics in the Life Sciences, OSA Technical Digest (online) (Optica Publishing Group, 2013), paper JW3B.4.

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Abstract

We study uptake of gold nanoparticles by cancer cells. By laser-induced heating we control escape of the gold nanoparticles from the endosomes into the cytoplasm and liberate miRNA coating the gold nanoparticles targeting gene silencing.

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