Combining backward-collected second- and third-harmonic signals, noninvasive optical biopsy of human skin is demonstrated. With backward collection geometry and energy-conservation characteristic of harmonic generations, this technique is ideal for future noninvasive clinical skin disease diagnosis.
© 2005 Optical Society of America
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.1870) Medical optics and biotechnology : Dermatology
(180.0180) Microscopy : Microscopy
(180.6900) Microscopy : Three-dimensional microscopy
S. Tai, T. Tsai, W. Lee, H. Huang, Y. Liao, K. Y. Zhan, H. Liu, and C. Sun, "Optical Biopsy of Human Skin with Backward-Collected Optical Harmonic Signals," in Conference on Lasers and Electro-Optics/Quantum Electronics and Laser Science and Photonic Applications Systems Technologies, Technical Digest (CD) (Optical Society of America, 2005), paper JThE28.
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