We investigated the excited-state ultra-fast dynamics of genetic fusions that link a Green Fluorescent Protein to an antibody fragment. Spectrally resolved pump-probe spectroscopy allowed us to discriminate between biolocally-active soluble and inactive insoluble antibody fusions.
© 2006 Optical Society of America
(320.0320) Ultrafast optics : Ultrafast optics
(320.7130) Ultrafast optics : Ultrafast processes in condensed matter, including semiconductors
(320.7150) Ultrafast optics : Ultrafast spectroscopy
P. Didier, L. Guidoni, and E. Weiss, "Ultrafast Excited-state Dynamics of Genetic Fusions: The Green Fluorescent Protein as a Folding Reporter," in Conference on Lasers and Electro-Optics/Quantum Electronics and Laser Science Conference and Photonic Applications Systems Technologies, Technical Digest (CD) (Optical Society of America, 2006), paper QMH1.
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