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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 37, Iss. 16 — Jun. 1, 1998
  • pp: 3426–3431

Fiber-optic sensor system for rapid positioning of a microelectrode array

Peter G. LoPresti and Warren E. Finn  »View Author Affiliations


Applied Optics, Vol. 37, Issue 16, pp. 3426-3431 (1998)
http://dx.doi.org/10.1364/AO.37.003426


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Abstract

A fiber-optic intensity sensor has been developed for vertically positioning microelectrode arrays above the retina of a live frog. Closely spaced fibers illuminate and collect reflections from the retinal surface, and the output is electronically processed to drive an automated positioning circuit. Experimental and theoretical evaluations of fiber types and separation for both specular and diffuse reflectors, in vitro and in vivo, are presented, and multimode fibers on 125-μm centers are chosen for retinal experimentation. The sensor has applications in assessing spatial selectivity of stimulation of a multielectrode array and may be adaptable for lateral positioning.

© 1998 Optical Society of America

OCIS Codes
(000.1430) General : Biology and medicine
(060.2370) Fiber optics and optical communications : Fiber optics sensors
(170.3890) Medical optics and biotechnology : Medical optics instrumentation

History
Original Manuscript: October 7, 1997
Revised Manuscript: January 20, 1998
Published: June 1, 1998

Citation
Peter G. LoPresti and Warren E. Finn, "Fiber-optic sensor system for rapid positioning of a microelectrode array," Appl. Opt. 37, 3426-3431 (1998)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-37-16-3426

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