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Applied Optics

Applied Optics


  • Vol. 38, Iss. 10 — Apr. 1, 1999
  • pp: 2128–2137

Experimental and theoretical laser-Doppler frequency spectra of a tissuelike model of a human head with capillaries

Robert Lohwasser and Gerald Soelkner  »View Author Affiliations

Applied Optics, Vol. 38, Issue 10, pp. 2128-2137 (1999)

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Laser-Doppler flow measurements with penetration depths from 10 to 30 mm have been performed on a layered model of the human head consisting of a regular array of capillaries with diameters of 340 µm embedded in an epoxy matrix with tissuelike scattering and absorption properties. Monte Carlo simulations and an analytical approach based on diffusing wave spectroscopy have corroborated the measurements and have led to a quantitative description of flow in deep-lying tissue layers with regard to layers near the surface also. The results indicate that it may be possible to measure changes in cortical blood flow even in the presence of a well-perfused scalp.

© 1999 Optical Society of America

OCIS Codes
(170.3340) Medical optics and biotechnology : Laser Doppler velocimetry
(170.7050) Medical optics and biotechnology : Turbid media

Original Manuscript: September 14, 1998
Revised Manuscript: January 14, 1999
Published: April 1, 1999

Robert Lohwasser and Gerald Soelkner, "Experimental and theoretical laser-Doppler frequency spectra of a tissuelike model of a human head with capillaries," Appl. Opt. 38, 2128-2137 (1999)

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