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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 38, Iss. 19 — Jul. 1, 1999
  • pp: 4262–4265

Compensated Transillumination

Xingkun Wu and Gregory W. Faris  »View Author Affiliations


Applied Optics, Vol. 38, Issue 19, pp. 4262-4265 (1999)
http://dx.doi.org/10.1364/AO.38.004262


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Abstract

We demonstrate imaging through human tissue in vivo, using a new optical technique, compensated transillumination. Immersion in a scattering medium with absorption and scattering coefficients matched to the tissue is used for drastic improvement of image contrast. The immersion medium is composed of polymer microspheres and methylene blue dye. The optical properties of the medium are matched to those of the tissue by use of a frequency-domain measurement technique. Images of a human hand taken with this technique show the internal structure, including the outlines of bones. The mechanism for the contrast is likely the absence of blood between the bones.

© 1999 Optical Society of America

OCIS Codes
(170.0110) Medical optics and biotechnology : Imaging systems
(170.1610) Medical optics and biotechnology : Clinical applications
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5280) Medical optics and biotechnology : Photon migration
(170.7050) Medical optics and biotechnology : Turbid media

Citation
Xingkun Wu and Gregory W. Faris, "Compensated Transillumination," Appl. Opt. 38, 4262-4265 (1999)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-38-19-4262


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