OSA's Digital Library

Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 39, Iss. 19 — Jul. 1, 2000
  • pp: 3372–3379

Disease pattern recognition in infrared spectra of human sera with diabetes mellitus as an example

Wolfgang Petrich, Brion Dolenko, Johanna Früh, Manfred Ganz, Helmut Greger, Stephan Jacob, Franz Keller, Alexander E. Nikulin, Matthias Otto, Ortrud Quarder, Ray L. Somorjai, Arnulf Staib, Gerhard Werner, and Hans Wielinger  »View Author Affiliations


Applied Optics, Vol. 39, Issue 19, pp. 3372-3379 (2000)
http://dx.doi.org/10.1364/AO.39.003372


View Full Text Article

Enhanced HTML    Acrobat PDF (351 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

To benefit from the full information content of the mid-IR spectra of human sera, we directly related the overall shape of the spectra to the donors’ disease states. For this approach of disease pattern recognition we applied cluster analysis and discriminant analysis to the example of the disease states diabetes type 1, diabetes type 2, and healthy. In a binary, supervised classification of any pair of these disease states we achieved specificities and sensitivities of ∼80% within our data set.

© 2000 Optical Society of America

OCIS Codes
(070.5010) Fourier optics and signal processing : Pattern recognition
(170.1470) Medical optics and biotechnology : Blood or tissue constituent monitoring
(170.1580) Medical optics and biotechnology : Chemometrics
(170.1610) Medical optics and biotechnology : Clinical applications
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(300.6390) Spectroscopy : Spectroscopy, molecular

History
Original Manuscript: October 6, 1999
Revised Manuscript: March 30, 2000
Published: July 1, 2000

Citation
Wolfgang Petrich, Brion Dolenko, Johanna Früh, Manfred Ganz, Helmut Greger, Stephan Jacob, Franz Keller, Alexander E. Nikulin, Matthias Otto, Ortrud Quarder, Ray L. Somorjai, Arnulf Staib, Gerhard Werner, and Hans Wielinger, "Disease pattern recognition in infrared spectra of human sera with diabetes mellitus as an example," Appl. Opt. 39, 3372-3379 (2000)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-39-19-3372

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited