Experimental Measurement of Corneal Haze After Excimer Laser Keratectomy
Applied Optics, Vol. 40, Issue 10, pp. 1727-1734 (2001)
http://dx.doi.org/10.1364/AO.40.001727
Acrobat PDF (4235 KB)
Abstract
We developed a model of corneal haze following photorefractive keratectomy (PRK) in Iber Braun hens and studied optical properties. The animals underwent PRK for −9.0 diopters of myopia and were divided into groups based on treatment with different wound-healing modulators. At different time points postoperatively, we evaluated haze by slit-lamp microscopy. An experimental device was developed to measure transmittance spatial maps and forward scattering of He–Ne laser light in the excised corneas. Subjective and objective haze measures were compared for each group at the different times. Keratocyte densities were determined by optical microscopy and keratocyte sizes by electron microscopy. The agreement between experimental results and a simple numerical model of scattering suggests that increases in stromal keratocyte density after PRK might explain the degree of corneal haze.
© 2001 Optical Society of America
[Optical Society of America ]
OCIS Codes
(170.1020) Medical optics and biotechnology : Ablation of tissue
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(290.5820) Scattering : Scattering measurements
Citation
Juan A. del Val, Sonia Barrero, Bety Yãez, Jesús Merayo, Juan A. Aparicio, Víctor R. González, José C. Pastor, and Santiago Mar, "Experimental Measurement of Corneal Haze After Excimer Laser Keratectomy," Appl. Opt. 40, 1727-1734 (2001)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-40-10-1727
You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
Related Journal Articles 
- Theory of a fixed scatterer embedded in a turbid medium: numerical results (JOSAA)
- Light-scattering properties of undiluted human blood subjected to simple shear (JOSAA)
- Theory of a fixed scatterer embedded in a turbid medium (JOSAA)
- Fluorescence Measurement in Thick Tissue Layers by Linear or Nonlinear Long-Wavelength Excitation (AO)
- Mechanisms of Light Scattering from Biological Cells Relevant to Noninvasive Optical-Tissue Diagnostics (AO)
Related Conference Papers
- Accelerated reverse-path Monte Carlo model to simulate fluorescence in layered tissue
- Fractal Mechanisms of Light Scattering in Biological Tissue and Cells
- A Novel Monte Carlo Simulation of Light Transport in the Human Finger towards Non-Invasive Measurement of Blood Hemoglobin Concentration
- Imaging Based Tissue Optics: Parallel Monte Carlo Modeling and Phantom Measurements
- Selective Damage of Coloration Centers Inhomogeneously Distributed in Skin by Nanosecond Near-IR Laser Pulses
« Previous Article | Next Article »
OSA is a member of 