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Applied Optics

Applied Optics


  • Vol. 41, Iss. 19 — Jul. 1, 2002
  • pp: 3816–3826

Volume image reconstruction for diffuse optical tomography

Uwe Hampel, Eckhard Schleicher, and Richard Freyer  »View Author Affiliations

Applied Optics, Vol. 41, Issue 19, pp. 3816-3826 (2002)

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Optical tomography is a potential diagnostic method for visualizing optical properties of tissues in vivo. We present an optical tomography method that has been designed for imaging of the human testes, particularly for spectroscopic tumor differentiation. In this application we need to compute three-dimensional distributions of the optical contrast (absorption coefficient) in the tissue in real time. Thus we have given special care to elaborate an efficient inverse algorithm that takes the limitations of spatial resolution and data space point density into account. Our inverse solution is based on a linearization approach and a dedicated object space discretization. Furthermore, we introduce the concept of fuzzy voxels, which enables a reconstruction-inherent image smoothing.

© 2002 Optical Society of America

OCIS Codes
(100.3010) Image processing : Image reconstruction techniques
(100.3190) Image processing : Inverse problems
(110.6960) Imaging systems : Tomography
(170.3880) Medical optics and biotechnology : Medical and biological imaging

Original Manuscript: September 5, 2001
Revised Manuscript: January 17, 2002
Published: July 1, 2002

Uwe Hampel, Eckhard Schleicher, and Richard Freyer, "Volume image reconstruction for diffuse optical tomography," Appl. Opt. 41, 3816-3826 (2002)

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