OSA's Digital Library

Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 42, Iss. 16 — Jun. 1, 2003
  • pp: 2881–2887

Monte Carlo prediction of near-infrared light propagation in realistic adult and neonatal head models

Yuich Fukui, Yusaku Ajichi, and Eiji Okada  »View Author Affiliations


Applied Optics, Vol. 42, Issue 16, pp. 2881-2887 (2003)
http://dx.doi.org/10.1364/AO.42.002881


View Full Text Article

Enhanced HTML    Acrobat PDF (275 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

In near-infrared spectroscopy and imaging, the sensitivity of the detected signal to brain activation and the volume of interrogated tissue are clinically important. Light propagation in adult and neonatal heads is strongly affected by the presence of a low-scattering cerebrospinal fluid layer. The effect of the heterogeneous structure of the head on light propagation in the adult brain is likely to be different from that in the neonatal brain because the thickness of the superficial tissues and the optical properties of the brain of the neonatal head are quite different from those of the adult head. In this study, light propagation in the two-dimensional realistic adult and neonatal head models, whose geometries are generated from a magnetic resonance imaging scan of the human heads, is predicted by Monte Carlo simulation. The sandwich structure, which is a low-scattering cerebrospinal fluid layer held between the high-scattering skull and gray matter, strongly affects light propagation in the brain of the adult head. The sensitivity of the absorption change in the gray matter is improved; however, the intensely sensitive region is confined to the shallow region of the gray matter. The high absorption of the neonatal brain causes a similar effect on light propagation in the head. The intensely sensitive region in the neonatal brain is confined to the gray matter; however, the spatial sensitivity profile penetrates into the deeper region of the white matter.

© 2003 Optical Society of America

OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.3890) Medical optics and biotechnology : Medical optics instrumentation

History
Original Manuscript: September 1, 2002
Revised Manuscript: December 13, 2002
Published: June 1, 2003

Citation
Yuich Fukui, Yusaku Ajichi, and Eiji Okada, "Monte Carlo prediction of near-infrared light propagation in realistic adult and neonatal head models," Appl. Opt. 42, 2881-2887 (2003)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-42-16-2881

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited