We present a noninvasive full-field method—laser speckle imaging (LSI)—for measuring the regional mesenteric blood flow without scanning. A system of LSI was designed and validated in a model experiment. Dynamics of regional blood flow in the rat mesentery under the influence of noradrenaline were monitored by this method. Spatial and temporal characteristics of the mesenteric blood-flow response were achieved with high resolution. These suggested that LSI might provide a new approach to microcirculation studies.
© 2003 Optical Society of America
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(120.6150) Instrumentation, measurement, and metrology : Speckle imaging
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5380) Medical optics and biotechnology : Physiology
Haiying Cheng, Qingming Luo, Zheng Wang, Hui Gong, Shangbin Chen, Wenxi Liang, and Shaoqun Zeng, "Efficient Characterization of Regional Mesenteric Blood Flow by Use of Laser Speckle Imaging," Appl. Opt. 42, 5759-5764 (2003)