OSA's Digital Library

Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 44, Iss. 10 — Apr. 1, 2005
  • pp: 1792–1797

In vivo fiber-optic confocal reflectance microscope with an injection-molded plastic miniature objective lens

Kristen Carlson, Matthew Chidley, Kung-Bin Sung, Michael Descour, Ann Gillenwater, Michele Follen, and Rebecca Richards-Kortum  »View Author Affiliations


Applied Optics, Vol. 44, Issue 10, pp. 1792-1797 (2005)
http://dx.doi.org/10.1364/AO.44.001792


View Full Text Article

Acrobat PDF (684 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

For in vivo optical diagnostic technologies to be distributed to the developed and developing worlds, optical imaging systems must be constructed of inexpensive components. We present a fiber-optic confocal reflectance microscope with a cost-effective injection-molded plastic miniature objective lens for in vivo imaging of human tissues in near real time. The measured lateral resolution is less than 2.2 µm, and the measured axial resolution is 10 µm. Confocal images of ex vivo cervical tissue biopsies and in vivo human lip taken at 15 frames/s demonstrate the microscope's capability of imaging cell morphology and tissue architecture.

© 2005 Optical Society of America

OCIS Codes
(170.1610) Medical optics and biotechnology : Clinical applications
(170.1790) Medical optics and biotechnology : Confocal microscopy
(170.2150) Medical optics and biotechnology : Endoscopic imaging
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4440) Medical optics and biotechnology : ObGyn
(170.4730) Medical optics and biotechnology : Optical pathology

Citation
Kristen Carlson, Matthew Chidley, Kung-Bin Sung, Michael Descour, Ann Gillenwater, Michele Follen, and Rebecca Richards-Kortum, "In vivo fiber-optic confocal reflectance microscope with an injection-molded plastic miniature objective lens," Appl. Opt. 44, 1792-1797 (2005)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-44-10-1792

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited