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Applied Optics

Applied Optics


  • Editor: Joseph N. Mait
  • Vol. 52, Iss. 33 — Nov. 20, 2013
  • pp: 8060–8066

Resolution of a Gen-2 handheld optical imager: diffuse and fluorescence imaging studies

Manuela Roman, Jean Gonzalez, Jennifer Carrasquilla, Sarah J. Erickson, Rad Akhter, and Anuradha Godavarty  »View Author Affiliations

Applied Optics, Vol. 52, Issue 33, pp. 8060-8066 (2013)

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A generation-2 (Gen-2) handheld optical imager capable of two-dimensional surface and three-dimensional tomographic imaging has recently been developed. Herein, the ability of the handheld imager to detect and resolve two targets under diffuse and fluorescence imaging conditions has been demonstrated via tissue phantom studies. Two-dimensional surface imaging studies demonstrated that two 0.96 cm diameter Indocyannine Green targets were detected and resolved 0.5cm apart (between edges) at a target depth of 1 cm during diffuse imaging and up to 2 cm depth during fluorescence imaging. Preliminary 3D tomographic imaging capability to resolve the two targets was also demonstrated, but requires extensive future studies.

© 2013 Optical Society of America

OCIS Codes
(110.3080) Imaging systems : Infrared imaging
(170.0110) Medical optics and biotechnology : Imaging systems
(110.0113) Imaging systems : Imaging through turbid media

ToC Category:
Imaging Systems

Original Manuscript: May 9, 2013
Revised Manuscript: October 8, 2013
Manuscript Accepted: October 22, 2013
Published: November 15, 2013

Virtual Issues
Vol. 9, Iss. 1 Virtual Journal for Biomedical Optics

Manuela Roman, Jean Gonzalez, Jennifer Carrasquilla, Sarah J. Erickson, Rad Akhter, and Anuradha Godavarty, "Resolution of a Gen-2 handheld optical imager: diffuse and fluorescence imaging studies," Appl. Opt. 52, 8060-8066 (2013)

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