OSA's Digital Library

Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 28, Iss. 6 — Mar. 15, 1989
  • pp: 1115–1121

Rod increment thresholds in cone-rod dystrophy

David W. Yates, Deborah J. Derlacki, David R. Pepperberg, Kenneth R. Alexander, and Gerald A. Fishman  »View Author Affiliations


Applied Optics, Vol. 28, Issue 6, pp. 1115-1121 (1989)
http://dx.doi.org/10.1364/AO.28.001115


View Full Text Article

Enhanced HTML    Acrobat PDF (888 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

Rod system increment threshold functions (ITFs) were studied in patients with cone–rod dystrophy (CRD). Rod thresholds (It) for a 104-min, 500-nm test stimulus (TS), superimposed on an 11° long wavelength background (luminance Ib), were measured in eleven CRD patients and fourteen normal subjects. Thresholds in normals were also measured using a 7-min TS. A modified version of Weber’s law [ log I t = log K   +  log ( I b n   + c ) ] was fitted to the data from each subject and test condition to yield a description of the ITF in terms of the free parameters K, c, and n. Four of the CRD patients exhibited an abnormally high absolute threshold; of these, two showed abnormalities in K and c consistent with a reduced efficiency of quantum capture by the rods. Abnormalities in the ITFs of CRD patients did not resemble the effect of reducing the diameter of the TS from 104 to 7 min in normals. This suggests that threshold abnormalities in the CRD patients did not result from altered spatial summation. The results illustrate use of a parametric representation of the ITF to evaluate the loss of sensitivity in visual disorders.

© 1989 Optical Society of America

History
Original Manuscript: June 2, 1988
Published: March 15, 1989

Citation
David W. Yates, Deborah J. Derlacki, David R. Pepperberg, Kenneth R. Alexander, and Gerald A. Fishman, "Rod increment thresholds in cone-rod dystrophy," Appl. Opt. 28, 1115-1121 (1989)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-28-6-1115

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited