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Applied Optics

Applied Optics


  • Vol. 29, Iss. 30 — Oct. 20, 1990
  • pp: 4481–4488

Diffusive optical fiber ends for photodynamic therapy: manufacture and analysis

Lennart Hasselgren, Sheila Galt, and Sverker Hard  »View Author Affiliations

Applied Optics, Vol. 29, Issue 30, pp. 4481-4488 (1990)

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Simple, diffusive optical fiber end light distributors for photodynamic therapy were manufactured and analyzed. The scattering properties were experimentally studied with respect to various design parameters. Computer simulations confirmed the measured parameter dependence, displaying the strength of the model. The best manufactured fiber end produced an almost uniform irradiance at a radial distance of one-third of the fiber end length.

© 1990 Optical Society of America

Original Manuscript: November 3, 1989
Published: October 20, 1990

Lennart Hasselgren, Sheila Galt, and Sverker Hard, "Diffusive optical fiber ends for photodynamic therapy: manufacture and analysis," Appl. Opt. 29, 4481-4488 (1990)

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  1. J. D. Spikes, G. Jori, “Photodynamic Therapy of Tumors and Other Diseases Using Porphyrines,” Lasers Med. Sci. 2, 3–14 (1987). [CrossRef]
  2. M. Arnfield, S. Gonzalez, P. Lea, J. Tulip, M. McPhee, “Cylindrical Irradiator Fiber Tip for Photodynamic Therapy,” Lasers Surgery Med. 6, 150–154 (1986). [CrossRef]
  3. P. Lenz, “Light Distributor for Endoscopic Photochemotherapy of Tumors,” Appl. Opt. 26, 4452–4456 (1987). [CrossRef] [PubMed]
  4. Accurate calculation of the parameter k is quite complicated and would have to include consideration of particle size distribution, surface roughness/inhomogeneity, multiple scattering, and Fresnel reflection of scattered light.

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