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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 33, Iss. 31 — Nov. 1, 1994
  • pp: 7397–7405

Optical properties of normal and carcinomatous bronchial tissue

Jianan Qu, Calum MacAulay, Stephen Lam, and Branko Palcic  »View Author Affiliations


Applied Optics, Vol. 33, Issue 31, pp. 7397-7405 (1994)
http://dx.doi.org/10.1364/AO.33.007397


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Abstract

To understand better the optical characteristics and autofluorescence properties of normal and carcinomatous bronchial tissue, we measured the absorption coefficient, scattering coefficient, and anisotropy factor from 400 to 700 nm. We made the measurements by using an integrating sphere with a collimated white-light beam to measure total reflectance and transmittance of samples. The unscattered transmittance of the samples was measured through polarized on-axis light detection. The inverse adding-doubling solution was utilized to solve the equation of radiative transfer and to determine the absorption coefficient and reduced scattering coefficient. The scattering coefficient and anisotropy factor were derived from the unscattered transmittance of the sample and the reduced scattering coefficient. The measured parameters allow us to simulate photon propagation in normal bronchial and tumoral tissue by using Monte Carlo modeling.

© 1994 Optical Society of America

History
Original Manuscript: November 10, 1993
Revised Manuscript: March 30, 1994
Published: November 1, 1994

Citation
Jianan Qu, Calum MacAulay, Stephen Lam, and Branko Palcic, "Optical properties of normal and carcinomatous bronchial tissue," Appl. Opt. 33, 7397-7405 (1994)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-33-31-7397

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