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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 35, Iss. 22 — Aug. 1, 1996
  • pp: 4533–4540

Time-resolved imaging on a realistic tissue phantom: μs′ and μa images versus time-integrated images

R. Cubeddu, A. Pifferi, P. Taroni, A. Torricelli, and G. Valentini  »View Author Affiliations


Applied Optics, Vol. 35, Issue 22, pp. 4533-4540 (1996)
http://dx.doi.org/10.1364/AO.35.004533


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Abstract

A method is proposed by which we construct images through turbid media, plotting directly either the transport-scattering coefficient μs′ or the absorption coefficient μa . These optical parameters are obtained from the best fit of the time-resolved transmittance curves with a diffusion model. Measurements were performed with a time-correlated single-photon counting system on realistic tissue phantoms simulating a tumor mass within a breast. Images were obtained with an incident power of <1 mW and an acquisition time of 1 s/point. Comparison of μs′ and μa images with time-integrated images constructed from the same experimental data shows that the fitting method discriminates between scattering and absorption inhomogeneities and improves image quality for scattering but not for absorption inhomogeneities.

© 1996 Optical Society of America

History
Original Manuscript: May 30, 1995
Revised Manuscript: February 23, 1996
Published: August 1, 1996

Citation
R. Cubeddu, A. Pifferi, P. Taroni, A. Torricelli, and G. Valentini, "Time-resolved imaging on a realistic tissue phantom: μs′ and μa images versus time-integrated images," Appl. Opt. 35, 4533-4540 (1996)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-35-22-4533


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