A method is proposed by which we construct images through turbid media, plotting directly either the transport-scattering coefficient μs ′ or the absorption coefficient μa. These optical parameters are obtained from the best fit of the time-resolved transmittance curves with a diffusion model. Measurements were performed with a time-correlated single-photon counting system on realistic tissue phantoms simulating a tumor mass within a breast. Images were obtained with an incident power of <1 mW and an acquisition time of 1 s/point. Comparison of μs ′ and μa images with time-integrated images constructed from the same experimental data shows that the fitting method discriminates between scattering and absorption inhomogeneities and improves image quality for scattering but not for absorption inhomogeneities.
© 1996 Optical Society of America
R. Cubeddu, A. Pifferi, P. Taroni, A. Torricelli, and G. Valentini, "Time-resolved imaging on a realistic tissue phantom: μs′ and μa images versus time-integrated images," Appl. Opt. 35, 4533-4540 (1996)