We describe the use of microlenses as amplification for CCD-based detection devices. The possible amplification of a signal in a reaction chamber of a nanoplate is estimated with a first-order approximation. This value was proved with a commercially available microlens and with a specially constructed microlens array made of glass hemispheres. Possible applications of this approach to amplification are given.
© 1998 Optical Society of America
Original Manuscript: August 21, 1997
Revised Manuscript: November 24, 1997
Published: April 1, 1998
Gregor Schlingloff, Hans-Jürgen Kiel, and Andreas Schober, "Microlenses as amplification for CCD-based detection devices for screening applications in biology, biochemistry, and chemistry," Appl. Opt. 37, 1930-1934 (1998)