We have developed a methodology that can be used in reconstruction algorithms to quantify the optical coefficients and the geometrical cross section of a weakly abnormal optical target embedded in an otherwise homogeneous medium. This novel procedure uses different time-dependent point-spread functions to analyze the diffusive and absorptive contrasts obtained from time-of-flight measurements. Data obtained from time-resolved transillumination of a tissuelike phantom are used to test the accuracy of this new deconvolution methodology.
© 1998 Optical Society of America
(100.1830) Image processing : Deconvolution
Original Manuscript: June 30, 1997
Revised Manuscript: November 4, 1997
Published: April 1, 1998
Amir H. Gandjbakhche, Victor Chernomordik, Jeremy C. Hebden, and Ralph Nossal, "Time-dependent contrast functions for quantitative imaging in time-resolved transillumination experiments," Appl. Opt. 37, 1973-1981 (1998)