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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 37, Iss. 13 — May. 1, 1998
  • pp: 2788–2797

Optical Scattering Properties of Soft Tissue: A Discrete Particle Model

Joseph M. Schmitt and Gitesh Kumar  »View Author Affiliations


Applied Optics, Vol. 37, Issue 13, pp. 2788-2797 (1998)
http://dx.doi.org/10.1364/AO.37.002788


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Abstract

We introduce a micro-optical model of soft biological tissue thatpermits numerical computation of the absolute magnitudes of itsscattering coefficients. A key assumption of the model is that therefractive-index variations caused by microscopic tissue elements canbe treated as particles with sizes distributed according to a skewedlog-normal distribution function. In the limit of an infinitelylarge variance in the particle size, this function has the samepower-law dependence as the volume fractions of the subunits of anideal fractal object. To compute a complete set of opticalcoefficients of a prototypical soft tissue (single-scatteringcoefficient, transport scattering coefficient, backscatteringcoefficient, phase function, and asymmetry parameter), we apply Mietheory to a volume of spheres with sizes distributed according to thetheoretical distribution. A packing factor is included in thecalculation of the optical cross sections to account for correlatedscattering among tightly packed particles. The results suggest thatthe skewed log-normal distribution function, with a shape specified bya limiting fractal dimension of 3.7, is a valid approximation of thesize distribution of scatterers in tissue. In the wavelength range 600 ≤ λ ≤ 1400 nm, the diameters of the scatterers thatcontribute most to backscattering were found to be significantlysmaller (λ/4–λ/2) than the diameters of the scatterersthat cause the greatest extinction of forward-scattered light(3–4λ).

© 1998 Optical Society of America

OCIS Codes
(170.6930) Medical optics and biotechnology : Tissue
(290.0290) Scattering : Scattering
(350.4990) Other areas of optics : Particles

Citation
Joseph M. Schmitt and Gitesh Kumar, "Optical Scattering Properties of Soft Tissue: A Discrete Particle Model," Appl. Opt. 37, 2788-2797 (1998)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-37-13-2788

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