OSA's Digital Library

Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 37, Iss. 4 — Feb. 1, 1998
  • pp: 772–778

Determination of tissue optical properties from diffuse reflectance profiles by multivariate calibration

Jan S. Dam, Peter E. Andersen, Torben Dalgaard, and Paul Erik Fabricius  »View Author Affiliations


Applied Optics, Vol. 37, Issue 4, pp. 772-778 (1998)
http://dx.doi.org/10.1364/AO.37.000772


View Full Text Article

Enhanced HTML    Acrobat PDF (179 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

We describe a method for determining the reduced scattering and absorption coefficients of turbid biological media from the spatially resolved diffuse reflectance. A Sugeno Fuzzy Inference System in conjunction with data preprocessing techniques is employed to perform multivariate calibration and prediction on reflectance data generated by Monte Carlo simulations. The preprocessing consists of either a principal component analysis or a new, extended curve-fitting procedure originating from diffusion theory. Prediction tests on reflectance data with absorption coefficients between 0.04 and 0.06 mm-1 and reduced scattering coefficients between 0.45 and 0.99 mm-1 show the root-mean-square error of this method to be 0.25% for both coefficients. With reference to practical applications, we also describe how the prediction accuracy is affected by using relative instead of absolute reflectance data, by imposing measurement noise on the reflectance data, and by changing the number and the position of detectors.

© 1998 Optical Society of America

OCIS Codes
(120.4570) Instrumentation, measurement, and metrology : Optical design of instruments
(160.4760) Materials : Optical properties
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.7050) Medical optics and biotechnology : Turbid media
(200.4260) Optics in computing : Neural networks

History
Original Manuscript: March 17, 1997
Revised Manuscript: July 2, 1997
Published: February 1, 1998

Citation
Jan S. Dam, Peter E. Andersen, Torben Dalgaard, and Paul Erik Fabricius, "Determination of tissue optical properties from diffuse reflectance profiles by multivariate calibration," Appl. Opt. 37, 772-778 (1998)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-37-4-772

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited