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Applied Optics

Applied Optics


  • Vol. 38, Iss. 16 — Jun. 1, 1999
  • pp: 3636–3643

Influence of Optical Aberrations on Laser-Induced Plasma Formation in Water and their Consequences for Intraocular Photodisruption

Alfred Vogel, Kester Nahen, Dirk Theisen, Reginald Birngruber, Robert J. Thomas, and Benjamin A. Rockwell  »View Author Affiliations

Applied Optics, Vol. 38, Issue 16, pp. 3636-3643 (1999)

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The influence of spherical aberrations on laser-induced plasma formation in water by 6-ns Nd:YAG laser pulses was investigated for focusing angles that are used in intraocular microsurgery. Waveform distortions of 5.5λ and 18.5λ between the optical axis and the 1/e2 irradiance values of the laser beam were introduced by replacement of laser achromats in the delivery system by planoconvex lenses. Aberrations of 18.5λ increased the energy threshold for plasma formation by a factor of 8.5 compared with the optimized system. The actual irradiance threshold for optical breakdown was determined from the threshold energy in the optimized system and the spot size measured with a knife-edge technique. For aberrations of 18.5λ the irradiance threshold was 48 times larger than the actual threshold when it was calculated by use of the diffraction-limited spot size but was 35 times smaller when it was calculated by use of the measured spot size. The latter discrepancy is probably due to hot spots in the focal region of the aberrated laser beam. Hence the determination of the optical-breakdown threshold in the presence of aberrations leads to highly erroneous results. In the presence of aberrations the plasmas are as much as 3 times longer and the transmitted energy is 17–20 times higher than without aberrations. Aberrations can thus strongly compromise the precision and the safety of intraocular microsurgery. They can further account for a major part of the differences in the breakdown-threshold and the plasma-transmission values reported in previous investigations.

© 1999 Optical Society of America

OCIS Codes
(140.3440) Lasers and laser optics : Laser-induced breakdown
(170.4470) Medical optics and biotechnology : Ophthalmology
(220.1010) Optical design and fabrication : Aberrations (global)
(350.3390) Other areas of optics : Laser materials processing
(350.5400) Other areas of optics : Plasmas

Alfred Vogel, Kester Nahen, Dirk Theisen, Reginald Birngruber, Robert J. Thomas, and Benjamin A. Rockwell, "Influence of Optical Aberrations on Laser-Induced Plasma Formation in Water and their Consequences for Intraocular Photodisruption," Appl. Opt. 38, 3636-3643 (1999)

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  1. S. J. Gitomer and R. D. Jones, “Laser-produced plasmas in medicine,” IEEE Trans. Plasma Sci. 19, 1209–1219 (1991).
  2. A. Vogel, “Nonlinear absorption: intraocular microsurgery and laser lithotripsy,” Phys. Med. Biol. 42, 895–912 (1997).
  3. M. R. Prince, G. M. LaMuraglia, P. Teng, T. F. Deutsch, and R. R. Anderson, “Preferential ablation of calcified arterial plaque with laser-induced plasmas,” IEEE J. Quantum Electron. QE-23, 1783–1786 (1987).
  4. R. F. Steinert and C. A. Puliafito, The Nd:YAG Laser in Ophthalmology (Saunders, Philadelphia, Pa., 1985).
  5. F. Fankhauser and S. Kwasniewska, “Neodymium:yttrium-aluminium-garnet laser,” in Ophthalmic Lasers, 3rd ed., F. A. L’Esperance, ed. (Mosby, St. Louis, Mo., 1989), pp. 781–886.
  6. A. Vogel, P. Schweiger, A. Frieser, M. Asiyo, and R. Birngruber, “Intraocular Nd:YAG laser surgery: light–tissue interaction, damage range, and reduction of collateral effects,” IEEE J. Quantum Electron. 26, 2240–2260 (1990).
  7. C. P. Cain, C. D. DiCarlo, B. A. Rockwell, P. K. Kennedy, G. N. Noojin, D. J. Stolarski, D. X. Hammer, C. A. Toth, and W. P. Roach, “Retinal damage and laser-induced breakdown produced by ultrashort-pulse lasers,” Graefe’s Arch. Clin. Exp. Ophthalmol. 234 Suppl. 1, S28–S37 (1996).
  8. A. Vogel, S. Busch, K. Jungnickel, and R. Birngruber, “Mechanisms of intraocular photodisruption with picosecond and nanosecond laser pulses,” Lasers Surg. Med. 15, 32–43 (1994).
  9. A. Vogel, K. Nahen, and D. Theisen, “Plasma formation in water by picosecond and nanosecond Nd:YAG laser pulses. Part I. Optical breakdown at threshold and superthreshold irradiance,” IEEE J. Select. Topics Quantum Electron. 2, 847–860 (1997).
  10. K. Nahen and A. Vogel, “Plasma formation in water by picosecond and nanosecond Nd:YAG laser pulses. Part II. Plasma transmission, scattering and reflection,” IEEE J. Select. Topics Quantum Electron. 2, 861–871 (1997).
  11. F. W. Campbell and R. W. Gubish, “Optical quality of the human eye,” J. Physiol. (London) 186, 558–578 (1966).
  12. W. M. Rosenblum and J. L. Christensen, “Objective and subjective spherical aberration measurement of the human eye,” Progr. Opt. 13, 69–91 (1976).
  13. J. Liang, B. Grimm, S. Goelz, and J. Bille, “Objective measurement of wave aberrations of the human eye with the use of a Hartmann–Shack wave-front sensor,” J. Opt. Soc. Am. A 11, 1949–1957 (1994).
  14. P. Artal and A. Guirao, “Contributions of the cornea and the lens to the aberrations of the human eye,” Opt. Lett. 23, 1713–1715 (1998).
  15. L. D. Santana Haro, J. C. Dainty, “Single-pass measurements of the wave-front aberrations of the human eye by use of retinal lipofuscin autofluorescence,” Opt. Lett. 24, 61–63 (1999).
  16. H. P. Loertscher, “Laser-induced breakdown for ophthalmic applications,” in YAG Laser Ophthalmic Microsurgery, S. C. Trokel, ed. (Appleton-Century-Crofts, Norwalk, Conn., 1983), pp. 39–66.
  17. R. F. Steinert and C. A. Puliafito, “Plasma formation and shielding by three ophthalmic neodymium-YAG lasers,” Am. J. Ophthalmol. 96, 427–434 (1983).
  18. R. F. Steinert, C. A. Puliafito, and C. Kittrell, “Plasma shielding by Q-switched and mode-locked Nd:YAG lasers,” Ophthalmology 90, 1003–1006 (1983).
  19. F. Docchio, C. A. Sacchi, and J. Marshall, “Experimental investigation of optical breakdown thresholds in ocular media under single pulse irradiation with different pulse durations,” Lasers Ophthalmol. 1, 83–93 (1986).
  20. M. R. C. Capon, F. Docchio, and J. Mellerio, “Nd:YAG laser photodisruption: an experimental investigation on shielding and multiple plasma formation,” Graefes Arch. Clin. Exp. Ophthalmol. 226, 362–366 (1988).
  21. F. Docchio and C. A. Sacchi, “Shielding properties of laser-induced plasmas in ocular media irradiated by single Nd:YAG pulses of different durations,” Invest. Ophthalmol. Visual Sci. 29, 437–443 (1988).
  22. F. Docchio, “Spatial and temporal dynamics of light attenuation and transmission by plasmas induced in liquids by nanosecond Nd:YAG laser pulses,” Nouv. Cimento 13, 87–98 (1991).
  23. S. A. Boppart, C. A. Toth, W. P. Roach, and B. A. Rockwell, “Shielding effectiveness of femtosecond laser-induced plasmas in ultrapure water,” in Laser Tissue Interaction IV, S. L. Jacques, ed., Proc. SPIE 1882, 347–354 (1993).
  24. D. X. Hammer, R. J. Thomas, G. D. Noojin, B. A. Rockwell, and A. Vogel, “Ultrashort pulse laser induced bubble creation thresholds in ocular media,” in Laser Tissue Interaction VI, S. L. Jacques, ed., Proc. SPIE 2391, 30–40 (1995).
  25. P. K. Kennedy, S. A. Boppart, D. X. Hammer, B. A. Rockwell, G. D. Noojin, and W. P. Roach, “A first-order model for computation of laser-induced breakdown thresholds in ocular and aqueous media. Part II. Comparison to experiment,” IEEE J. Quantum Electron. 31, 2250–2257 (1995).
  26. D. X. Hammer, E. D. Jansen, M. Frenz, G. D. Noojin, R. J. Thomas, J. Noack, A. Vogel, B. A. Rockwell, and A. J. Welch, “Shielding properties of laser-induced breakdown in water for pulse durations from 5 ns to 125 fs,” Appl. Opt. 36, 5630–5640 (1997).
  27. L. R. Evans and C. G. Morgan, “Lens aberration effects in optical-frequency breakdown of gases,” Phys. Rev. Lett. 22, 1099–1102 (1969).
  28. C. G. Morgan, “Laser-induced breakdown in gases,” Rep. Prog. Phys. 38, 621–665 (1975).
  29. W. L. Smith, J. H. Bechtel, and N. Bloembergen, “Dielectric-breakdown threshold and nonlinear-refractive-index measurements with picosecond laser pulses,” Phys. Rev. B 12, 706–714 (1975).
  30. P. Rol, F. Fankhauser, and S. Kwasniewska, “Evaluation of contact lenses for laser therapy. Part I,” Lasers Ophthalmol. 1, 1–20 (1986).
  31. A. E. Siegman, M. W. Sasnett, and T. F. Johnston, “Choice of clip levels for beam width measurements using knife-edge techniques,” IEEE J. Quantum Electron. 27, 1098–1104 (1991).
  32. M. W. Sasnett, “Propagation of multimode laser beams—the M2 factor,” in The Physics and Technology of Laser Resonators, D. R. Hall and P. E. Jackson, eds. (Adam Hilger, New York, 1989), pp. 94–105.
  33. J. M. Aaron, C. L. M. Ireland, and C. G. Morgan, “Aberration effects in the interaction of focused laser beams with matter,” J. Appl. Phys. J. Phys. D 7, 1907–1917 (1974).
  34. A. Vogel, S. Busch, and U. Parlitz, “Shock wave emission and cavitation bubble generation by picosecond and nanosecond optical breakdown in water,” J. Acoust. Soc. Am. 100, 148–165 (1996).
  35. A. Vogel, W. Hentschel, J. Holzfuss, and W. Lauterborn, “Cavitation bubble dynamics and acoustic transient generation in ocular surgery with pulsed neodymium:YAG lasers,” Ophthalmology 93, 1259–1269 (1986).
  36. J. W. Rayleigh, “On the pressure developed in a liquid during the collapse of a spherical cavity,” Philos. Mag. 34, 94–98 (1917).
  37. A. Vogel, J. Noack, K. Nahen, D. Theisen, S. Busch, U. Parlitz, D. X. Hammer, G. D. Noojin, B. A. Rockwell, and R. Birngruber, “Energy balance of optical breakdown in water at nanosecond to femtosecond time scales,” Appl. Phys. B. 68, 271–280 (1999).
  38. F. Docchio, P. Regondi, M. R. C. Capone, and J. Mellerio, “Study of the temporal and spatial dynamics of plasmas induced in liquids by nanosecond Nd:YAG laser pulses. 1: analysis of the plasma starting times,” Appl. Opt. 27, 3661–3668 (1988).
  39. A. Vogel and W. Lauterborn, “Acoustic transient generation by laser-produced cavitation bubbles near solid boundaries,” J. Acoust. Soc. Am. 84, 719–731 (1988).
  40. F. Fankhauser, U. Dürr, H. Giger, P. Rol, and S. Kwasniewska, “Lasers, optical systems and safety in ophthalmology: a review,” Graefes Arch. Clin. Exp. Ophthalmol. 234, 473–487 (1996).

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