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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 38, Iss. 22 — Aug. 1, 1999
  • pp: 4951–4958

Absorption Distribution of an Optical Beam Focused into a Turbid Medium

Lihong V. Wang and Gan Liang  »View Author Affiliations


Applied Optics, Vol. 38, Issue 22, pp. 4951-4958 (1999)
http://dx.doi.org/10.1364/AO.38.004951


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Abstract

The focusing of light into a turbid medium was studied with Monte Carlo simulations. Focusing was found to have a significant effect on the absorption distribution in turbid media when the depth of the focal point (the distance between the focal point and the surface of the turbid media) was less than or comparable with the transport mean free path. Focusing could significantly increase the peak absorption and narrow the absorption distribution. As the depth of the focal point increased, the peak absorption decreased, and the depth of peak absorption increased initially but quickly reached a plateau that was less than the transport mean free path. A refractive-index-mismatched boundary between the ambient medium and the turbid medium deteriorated the focusing effect, increased the absorption near the boundary, lowered the peak absorption, and broadened the absorption distribution.

© 1999 Optical Society of America

OCIS Codes
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.7050) Medical optics and biotechnology : Turbid media
(290.7050) Scattering : Turbid media

Citation
Lihong V. Wang and Gan Liang, "Absorption Distribution of an Optical Beam Focused into a Turbid Medium," Appl. Opt. 38, 4951-4958 (1999)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-38-22-4951


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References

  1. A. H. Hielscher, R. E. Alcouffe, and R. L. Barbour, “Comparison of finite-difference transport and diffusion calculations for photon migration in homogeneous and heterogeneous tissues,” Phys. Med. Biol. 43, 1285–1302 (1998).
  2. M. Schweiger and S. R. Arridge, “The finite-element method for the propagation of light in scattering media—frequency domain case,” Med. Phys. 24, 895–902 (1997).
  3. A. H. Gandjbakhche, G. H. Weiss, R. F. Bonner, and R. Nossal, “Photon path-length distributions for transmission through optically turbid slabs,” Phys. Rev. E 48, 810–818 (1993).
  4. L. T. Perelman, J. Wu, I. Itzkan, and M. S. Feld, “Photon migration in turbid media using path integrals,” Phys. Rev. Lett. 72, 1341–1344 (1994).
  5. A. Singh and K. P. Gopinathan, “Confocal microscopy—a powerful technique for biological research,” Curr. Sci. 74, 841–851 (1998).
  6. B. C. Wilson and G. A. Adam, “Monte Carlo model for the absorption and flux distributions of light in tissue,” Med. Phys. 10, 824–830 (1983).
  7. S. T. Flock, B. C. Wilson, D. R. Wyman, and M. S. Patterson, “Monte-Carlo modeling of light-propagation in highly scattering tissues I: model predictions and comparison with diffusion-theory,” IEEE Trans. Biomed. Eng. 36, 1162–1168 (1989).
  8. S. A. Prahl, M. Keijzer, S. L. Jacques, and A. J. Welch, “A Monte Carlo model of light propagation in tissue,” in Dosimetry of Laser Radiation in Medicine and Biology, G. J. Muller and D. H. Sliney, eds. Vol. IS5 of SPIE Institute Series (SPIE, Bellingham, Wash., 1989), pp. 102–111.
  9. S. L. Jacques and L.-H. Wang, “Monte Carlo modeling of light transport in tissues,” in Optical Thermal Response of Laser Irradiated Tissue, A. J. Welch and M. J. C. van Gemert, eds., (Plenum, New York, 1995), pp. 73–100.
  10. L.-H. Wang, S. L. Jacques, and L.-Q. Zheng, “MCML—Monte Carlo modeling of photon transport in multi-layered tissues,” Comp. Meth. Prog. Biomed. 47, 131–146 (1995). The MCML/CONV software package may be downloaded from URL:http://people.tamu.edu/~lwang.
  11. A. Sassaroli, C. Blumetti, F. Martelli, L. Alianelli, D. Contini, A. Ismaelli, and G. Zaccanti, “Monte Carlo procedure for investigating light propagation and imaging of highly scattering media,” Appl. Opt. 37, 7392–7400 (1997).
  12. E. Okada, M. Firbank, M. Schweiger, S. R. Arridge, M. Cope, and D. T. Delpy, “Theoretical and experimental investigation of near-infrared light propagation in a model of the adult head,” Appl. Opt. 36, 21–31 (1997).
  13. L.-H. Wang, S. L. Jacques, and L.-Q. Zheng, “CONV—convolution for responses to a finite diameter photon beam incident on multi-layered tissues,” Comp. Meth. Prog. Biomed. 54, 141–150 (1997).
  14. I. Lux and L. Koblinger, Monte Carlo Particle Transport Methods: Neutron and Photon Calculations (CRC Press, Boca Raton, Fla., 1991).
  15. C. Sturesson and S. Andersson-Engels, “Mathematical modeling of dynamic cooling and pre-heating, used to increase the depth of selective damage to blood vessels in laser treatment of port wine stains,” Phys. Med. Biol. 41, 413–428 (1996).
  16. C. G. A. Hoelen, F. F. M. Demul, R. Pongers, and A. Dekker, “Three-dimensional photoacoustic imaging of blood vessels in tissue,” Opt. Lett. 23, 648–650 (1998).

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