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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 38, Iss. 31 — Nov. 1, 1999
  • pp: 6661–6672

Optical and thermal characterization of albumin protein solders

Karen M. McNally, Brian S. Sorg, Naresh C. Bhavaraju, Mathieu G. Ducros, Ashley J. Welch, and Judith M. Dawes  »View Author Affiliations


Applied Optics, Vol. 38, Issue 31, pp. 6661-6672 (1999)
http://dx.doi.org/10.1364/AO.38.006661


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Abstract

The effect of temperature on the optical and thermal properties of pure and indocyanine green-doped albumin protein solders as a function of wavelength has been studied between 25 °C and 100 °C. An increase in the group refractive index by up to 4% and a decrease in absorption coefficient (∼800 nm) by up to 8%, after denaturing the solder specimens in a constant-temperature water bath at temperatures of 60–100 °C, were not significant. The reduced scattering coefficient, however, increased rapidly with temperature as the solder changed from being a highly nonscattering medium at room temperature to a highly scattering medium at temperatures close to 70 °C. The thermal conductivity, thermal diffusivity, and heat capacity increased by up to 30%, 15%, and 10%, respectively. Finally, the frequency factor and activation energy were measured to be 3.17 × 1056 s-1 and 3.79 × 105 J mol-1, respectively, for liquid protein solders (25% bovine serum albumin) and 3.50 × 1057 s-1 and 3.85 × 105 J mol-1, respectively, for solid protein solders (60% bovine serum albumin). Incorporation of dynamic optical and thermal properties into modeling studies of laser tissue interactions could have a significant influence on the determination of the expected zone of damage.

© 1999 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(120.6780) Instrumentation, measurement, and metrology : Temperature
(140.2020) Lasers and laser optics : Diode lasers
(160.4760) Materials : Optical properties
(170.6940) Medical optics and biotechnology : Tissue welding
(300.6190) Spectroscopy : Spectrometers

History
Original Manuscript: March 29, 1999
Revised Manuscript: July 19, 1999
Published: November 1, 1999

Citation
Karen M. McNally, Brian S. Sorg, Naresh C. Bhavaraju, Mathieu G. Ducros, Ashley J. Welch, and Judith M. Dawes, "Optical and thermal characterization of albumin protein solders," Appl. Opt. 38, 6661-6672 (1999)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-38-31-6661

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