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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 39, Iss. 28 — Oct. 1, 2000
  • pp: 5256–5261

Quantitative optical image reconstruction of turbid media by use of direct-current measurements

Nicusor Iftimia and Huabei Jiang  »View Author Affiliations


Applied Optics, Vol. 39, Issue 28, pp. 5256-5261 (2000)
http://dx.doi.org/10.1364/AO.39.005256


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Abstract

We present a detailed experimental study concerning quantitative optical property reconstruction of heterogeneous turbid media by use of absolute dc data only. We performed experiments by using tissuelike phantoms in both single-target and multitarget configurations in which variations in target size and optical contrast with the background were explored. Our results show that both scattering and absorption images can be reconstructed quantitatively by use of dc data only, whereas it was impossible to obtain such quantitative information in previously reported studies. We believe that this improvement is primarily a result of the realization of a novel data preprocessing/optimization scheme for accurately determining several critical parameters needed for reconstruction. The use of this data preprocessing/optimization scheme also eliminates the calibration reference measurement previously required for reconstruction. Experimental confirmation of this scheme is given in detail.

© 2000 Optical Society of America

OCIS Codes
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.3830) Medical optics and biotechnology : Mammography
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.6960) Medical optics and biotechnology : Tomography

History
Original Manuscript: March 7, 2000
Revised Manuscript: June 26, 2000
Published: October 1, 2000

Citation
Nicusor Iftimia and Huabei Jiang, "Quantitative optical image reconstruction of turbid media by use of direct-current measurements," Appl. Opt. 39, 5256-5261 (2000)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-39-28-5256


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References

  1. B. Tromberg, A. Yodh, E. Sevick-Muraca, D. Pine, “Diffusing photons in turbid media: introduction,” Appl. Opt. 36, 9 (1997). [CrossRef]
  2. A. Yodh, B. Tromberg, E. Sevick-Muraca, D. Pine, “Diffusing photons in turbid media: introduction,” J. Opt. Soc. Am. A 14, 136 (1997).
  3. B. W. Pogue, “Diffusion optical tomography: introduction,” Opt. Express 4, 1 (1999), http://epubs.osa.org/opticsexpress . [CrossRef]
  4. R. L. Barbour, H. Graber, J. Chang, S. Barbour, P. Koo, R. Aronson, “MRI-guided optical tomography: prospects and computation for a new imaging method,” IEEE Comput. Sci. Eng. 2, 63–77 (1995). [CrossRef]
  5. S. R. Arridge, M. Schweiger, “Image reconstruction in optical tomography,” Philos. Trans. R. Soc. London Ser. B 352, 717–726 (1997). [CrossRef]
  6. M. A. O’Leary, D. A. Boas, B. Chance, A. G. Yodh, “Experimental images of heterogeneous turbid media by frequency-domain diffusing-photon tomography,” Opt. Lett. 20, 426–428 (1995). [CrossRef] [PubMed]
  7. H. Jiang, K. D. Paulsen, U. L. Osterberg, B. W. Pogue, M. S. Patterson, “Simultaneous reconstruction of absorption and scattering profiles in turbid media from near-infrared frequency-domain data,” Opt. Lett. 20, 2128–2130 (1995). [CrossRef] [PubMed]
  8. H. Jiang, “Optical image reconstruction based on the third-order diffusion equations,” Opt. Express 4, 241–246 (1999), http://epubs.osa.org/opticsexpress . [CrossRef]
  9. W. Cai, S. Gayen, M. Xu, M. Zevallos, M. Alrubaiee, M. Lax, R. Alfano, “Optical tomographic image reconstruction from ultrafast time-sliced transmission measurements,” Appl. Opt. 38, 4237–4246 (1999). [CrossRef]
  10. S. B. Colak, D. Papaioannou, G. tHooft, M. vander Mark, H. Schomberg, J. Paasschens, J. Melissen, N. van Asten, “Tomographic image reconstruction from optical projections in light diffusing media,” Appl. Opt. 36, 180–213 (1997). [CrossRef] [PubMed]
  11. S. A. Walker, S. Fantini, E. Gratton, “Image reconstruction by backprojection from frequency-domain optical measurements in highly scattering media,” Appl. Opt. 36, 170–179 (1997). [CrossRef] [PubMed]
  12. B. W. Pogue, T. McBride, J. Prewitt, U. Osterberg, K. Paulsen, “Spatially variant regularization improves diffuse optical tomography,” Appl. Opt. 38, 2950–2961 (1999). [CrossRef]
  13. C. L. Matson, H. Liu, “Analysis of the forward problem with diffuse photon density waves in turbid media by use of a diffraction tomography model,” J. Opt. Soc. Am. A 16, 455–466 (1999). [CrossRef]
  14. J. Scotland, “Continuous-wave diffusion imaging,” J. Opt. Soc. Am. A 14, 275–279 (1997). [CrossRef]
  15. X. Cheng, D. Boas, “Diffuse optical reflection tomography with continuous-wave illumination,” Opt. Express 3, 118–123 (1998), http://epubs.osa.org/opticsexpress . [CrossRef]
  16. M. J. Eppstein, D. Dougherty, T. Troy, E. Sevick-Muraca, “Biomedical optical tomography using dynamic parameterization and Bayesian conditioning on photon migration measurements,” Appl. Opt. 38, 2138–2150 (1999). [CrossRef]
  17. J. C. Ye, K. Webb, R. Millane, T. Downar, “Modified distorted Born iterative method with an approximate Frechet derivative for optical diffusion tomography,” J. Opt. Soc. Am. A 16, 1814–1826 (1999). [CrossRef]
  18. K. D. Paulsen, H. Jiang, “Spatially varying optical property reconstruction using a finite-element diffusion equation approximation,” Med. Phys. 22, 691–702 (1995). [CrossRef] [PubMed]
  19. H. Jiang, K. Paulsen, U. Osterberg, B. Pogue, M. Patterson, “Optical image reconstruction using frequency-domain data: simulations and experiments,” J. Opt. Soc. Am. A 13, 253–266 (1996). [CrossRef]
  20. H. Jiang, K. Paulsen, U. Osterberg, M. Patterson, “Frequency-domain optical image reconstruction in heterogeneous media: an experimental study of single-target detectability,” Appl. Opt. 36, 52–63 (1997). [CrossRef] [PubMed]
  21. H. Jiang, K. Paulsen, U. Osterberg, M. Patterson, “Frequency-domain near-infrared photo diffusion imaging: initial evaluation in multitarget tissuelike phantoms,” Med. Phys. 25, 183–193 (1998). [CrossRef] [PubMed]
  22. H. Jiang, K. Paulsen, U. Osterberg, “Optical image reconstruction using DC data: simulations and experiments,” Phys. Med. Biol. 41, 1483–1498 (1996). [CrossRef] [PubMed]
  23. H. Jiang, K. Paulsen, U. Osterberg, M. Patterson, “Improved continuous light diffusion imaging in single- and multi-target tissuelike phantoms,” Phys. Med. Biol. 43, 675–693 (1998). [CrossRef] [PubMed]
  24. R. Kaskell, L. Svaasand, T. Tsay, T. Feng, M. McAdams, B. Tromberg, “Boundary conditions for the diffusion equation in radiative transfer,” J. Opt. Soc. Am. A 11, 2727–2741 (1994). [CrossRef]
  25. N. Iftimia, H. Jiang, “Development of a combined optical and fluorescence imaging system in frequency domain for breast cancer detection,” in Biomedical Topical Meetings, Postconference Digest, Trends in Optics and Photonics Series (Optical Society of America, Washington, D.C., 2000), pp. 383–385.

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