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Applied Optics

Applied Optics


  • Vol. 39, Iss. 31 — Nov. 1, 2000
  • pp: 5890–5897

Modeling of the rough-interface effect on a converging light beam propagating in a skin tissue phantom

Jun Q. Lu, Xin-Hua Hu, and Ke Dong  »View Author Affiliations

Applied Optics, Vol. 39, Issue 31, pp. 5890-5897 (2000)

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Light distribution in a strong turbid medium such as skin tissue depends on both the bulk optical properties and the profiles of the interfaces where mismatch in the refractive index occurs. We present recent results of a numerical investigation on the light distribution inside a human skin tissue phantom for a converging laser beam with a wavelength near 1 µm and its dependence on the roughness of the interfaces and index mismatch. The skin tissue is modeled by a two-layer structure, and within each layer the tissue is considered macroscopically homogeneous. The two interfaces that separate the epidermis from the ambient medium and the dermis are considered randomly rough. With a recently developed method of Monte Carlo simulation capable of treating inhomogeneous boundary conditions, light distributions in various cases of interface roughness and index mismatch are obtained, and their relevance to the measurements of optical parameters of the skin tissue and laser surgery under the skin surface are discussed.

© 2000 Optical Society of America

OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.1870) Medical optics and biotechnology : Dermatology
(170.6930) Medical optics and biotechnology : Tissue
(240.5770) Optics at surfaces : Roughness

Original Manuscript: April 20, 2000
Revised Manuscript: June 27, 2000
Published: November 1, 2000

Jun Q. Lu, Xin-Hua Hu, and Ke Dong, "Modeling of the rough-interface effect on a converging light beam propagating in a skin tissue phantom," Appl. Opt. 39, 5890-5897 (2000)

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  1. R. R. Anderson, J. A. Parrish, “The optics of human skin,” J. Invest. Dermotol. 77, 13–19 (1981). [CrossRef]
  2. M. J. C. van Gemert, S. L. Jacque, H. J. C. M. Sterenborg, W. M. Star, “Skin optics,” IEEE Trans. Biomed. Eng. 36, 1146–1154 (1989). [CrossRef] [PubMed]
  3. A. Ishimaru, Wave Propagation and Scattering in Random Media (Academic, New York, 1978), Vol. 1.
  4. B. C. Wilson, G. Adams, “A Monte Carlo model for the absorption and flux distributions of light in tissue,” Med. Phys. 10, 824–830 (1983). [CrossRef] [PubMed]
  5. M. Keijzer, S. T. Jacques, S. A. Prahl, A. J. Welch, “Light distributions in artery tissue: Monte Carlo simulations for finite-diameter laser beams,” Lasers Surg. Med. 9, 148–154 (1989). [CrossRef] [PubMed]
  6. R. Marchesini, C. Clemente, E. Pignoli, M. Brambilla, “Optical properties of in vitro epidermis and their possible relationship with optical properties of in vivo skin,” J. Photochem. Photobiol. B 16, 127–140 (1992). [CrossRef] [PubMed]
  7. R. Graaff, A. C. M. Dassel, M. H. Koelink, F. F. M. de Mul, J. G. Aarnoudse, W. G. Zijlstra, “Optical properties of human dermis in vitro and in vivo,” Appl. Opt. 32, 435–447 (1993). [CrossRef] [PubMed]
  8. J. M. Schmitt, G. X. Zhou, E. C. Walker, “Multilayer model of photon diffusion in skin,” J. Opt. Soc. Am. A 7, 2141–2153 (1990). [CrossRef] [PubMed]
  9. I. D. Miller, A. R. Veith, “Optical modelling of light distributions in skin tissue following laser irradiation,” Lasers Surg. Med. 13, 565–571 (1993). [CrossRef] [PubMed]
  10. W. Verkruysse, J. W. Pickering, J. F. Beek, M. Keijzer, M. J. C. van Germert, “Modeling the effect of wavelength on the pulsed dye laser treatment of port wine stains,” Appl. Opt. 32, 393–398 (1993). [CrossRef] [PubMed]
  11. M. Rajadhyaksha, R. R. Anderson, R. H. Webb, “Video-rate confocal scanning laser microscope for imaging human tissues in vivo,” Appl. Opt. 38, 2105–2115 (1999). [CrossRef]
  12. G. J. Tearney, M. E. Brezinski, J. F. Southern, B. E. Bouma, M. R. Hee, J. G. Fujimoto, “Determination of the refractive index of highly scattering human tissue by optical coherence tomography,” Opt. Lett. 21, 2258–2260 (1995). [CrossRef]
  13. X. H. Hu, “Efficient use of Q-switched lasers in the treatment of cutaneous lesions,” in Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems V, by R. R. Anderson, ed., Proc. SPIE2395, 586–591 (1995).
  14. Z. Song, K. Dong, X. H. Hu, J. Q. Lu, “Monte Carlo simulation of converging laser beams propagating in biological tissue,” Appl. Opt. 37, 2944–2949 (1999). [CrossRef]
  15. H. G. Burkitt, B. Young, J. W. Heath, Wheater’s Functional Histology, 3rd ed. (Longman Group, Edinburgh, 1993), Chap. 9.
  16. G. Plewig, T. Jansen, “Size and shape of corneocytes: variation with anatomic site and age,” in Bioengineering of the Skin: Skin Surface Imaging and Analysis, by K.-P. Wilhelm, P. Elsner, E. Berardesca, H. I. Maibach, eds. (CRC, Boca Raton, Fla., 1996), Chap. III-3.
  17. C. el Gammal, A. M. Kligman, S. el Gammal, “Anatomy of the skin surface,” in Bioengineering of the Skin: Skin Surface Imaging and Analysis, by K.-P. Wilhelm, P. Elsner, E. Berardesca, H. I. Mailbach, eds. (CRC, Boca Raton, Fla., 1996), Chap. I.
  18. N. Garcia, E. Stoll, “Monte Carlo calculation for electromagnetic wave scattering from random rough surfaces,” Phys. Rev. Lett. 52, 1798–1801 (1984). [CrossRef]
  19. A. A. Maradudin, T. Michel, A. R. McGurn, E. R. Mendez, “Enhanced backscattering of light from a random grating,” Ann. Phys. 203, 255–307 (1990). [CrossRef]
  20. P. Tran, A. A. Maradudin, “Scattering of a scalar beam from a two-dimensional randomly rough hard wall: enhanced backscattering,” Phys. Rev. B 45, 3936–3939 (1992). [CrossRef]
  21. P. Beckmann, A. Spizzichino, The Scattering of Electromagnetic Waves from Rough Surfaces (Pergamon, London, 1963), Chap. 3.
  22. J. Q. Lu, A. A. Maradudin, T. Michel, “Enhanced backscattering from a rough dielectric film on a reflecting substrate,” J. Opt. Soc. Am. B 8, 311–317 (1991). [CrossRef]
  23. V. G. Peters, D. R. Wyman, M. S. Patterson, G. L. Frank, “Optical properties of normal and diseased human breast tissues in the visible and near infrared,” Phys. Med. Biol. 35, 1317–1334 (1990). [CrossRef] [PubMed]
  24. Y. Du, M. Cariveau, G. W. Kalmus, J. Q. Lu, X. H. Hu, “Experimental study of optical properties of porcine skin dermis from 900 to 1500 nm,” in Optical Biopsy III, R. R. Alfano, ed., Proc. SPIE3917, 184–192 (2000). [CrossRef]

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