Instrumentation is described that is suitable for acquiring multisource, multidetector, time-series optical data at high sampling rates (up to 150 Hz) from tissues having arbitrary geometries. The design rationale, calibration protocol, and measured performance features are given for both a currently used, CCD-camera-based instrument and a new silicon-photodiode-based system under construction. Also shown are representative images that we reconstructed from data acquired in laboratory studies using the described CCD-based instrument.
© 2000 Optical Society of America
(170.1610) Medical optics and biotechnology : Clinical applications
(170.3830) Medical optics and biotechnology : Mammography
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.5380) Medical optics and biotechnology : Physiology
Christoph H. Schmitz, Harry L. Graber, Hengbin Luo, Imran Arif, Jai Hira, Yaling Pei, Avraham Bluestone, Sheng Zhong, Randy Andronica, Ira Soller, Nestor Ramirez, San-Lian S. Barbour, and Randall L. Barbour, "Instrumentation and Calibration Protocol for Imaging Dynamic Features in Dense-Scattering Media by Optical Tomography," Appl. Opt. 39, 6466-6486 (2000)