The eyes of all normal subjects undergo a continuous, low-amplitude, high-frequency tremor called ocular microtremor (OMT). A number of potential clinical applications of OMT have been identified, including the prediction of outcome in coma. To date, OMT has been investigated primarily with an eye-contacting piezoelectric probe. We describe a laser-based, noncontacting, interferometric technique for the measurement of OMT. The technique employs an in-plane-sensitive, phase-modulating speckle interferometer to detect the movement of the sclera, or white of the eye.
© 2001 Optical Society of America
(120.3930) Instrumentation, measurement, and metrology : Metrological instrumentation
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.4460) Medical optics and biotechnology : Ophthalmic optics and devices
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
Gerard Boyle, Davis Coakley, and Jim F. Malone, "Interferometry for ocular microtremor measurement," Appl. Opt. 40, 167-175 (2001)