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Applied Optics

Applied Optics


  • Vol. 40, Iss. 19 — Jul. 1, 2001
  • pp: 3288–3303

Design of near-infrared imaging probe with the assistance of ultrasound localization

Quing Zhu, Nan Guang Chen, Daqing Piao, Puyun Guo, and XiaoHui Ding  »View Author Affiliations

Applied Optics, Vol. 40, Issue 19, pp. 3288-3303 (2001)

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A total of 364 optical source–detector pairs were deployed uniformly over a 9 cm × 9 cm probe area initially, and then the total pairs were reduced gradually to 60 in experimental and simulation studies. For each source–detector configuration, three-dimensional (3-D) images of a 1-cm-diameter absorber of different contrasts were reconstructed from the measurements made with a frequency-domain system. The results have shown that more than 160 source–detector pairs are needed to reconstruct the absorption coefficient to within 60% of the true value and appropriate spatial and contrast resolution. However, the error in target depth estimated from 3-D images was more than 1 cm in all source–detector configurations. With the a priori target depth information provided by ultrasound, the accuracy of the reconstructed absorption coefficient was improved by 15% and 30% on average, and the beam width was improved by 24% and 41% on average for high- and low-contrast cases, respectively. The speed of reconstruction was improved by ten times on average.

© 2001 Optical Society of America

OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.3830) Medical optics and biotechnology : Mammography
(170.5270) Medical optics and biotechnology : Photon density waves
(170.7170) Medical optics and biotechnology : Ultrasound

Original Manuscript: September 20, 2000
Revised Manuscript: March 21, 2001
Published: July 1, 2001

Quing Zhu, Nan Guang Chen, Daqing Piao, Puyun Guo, and XiaoHui Ding, "Design of near-infrared imaging probe with the assistance of ultrasound localization," Appl. Opt. 40, 3288-3303 (2001)

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