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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 40, Iss. 31 — Nov. 1, 2001
  • pp: 5742–5747

Sensitive disk resonator photonic biosensor

Robert W. Boyd and John E. Heebner  »View Author Affiliations


Applied Optics, Vol. 40, Issue 31, pp. 5742-5747 (2001)
http://dx.doi.org/10.1364/AO.40.005742


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Abstract

We describe a photonic device based on a high-finesse, whispering-gallery-mode disk resonator that can be used for the detection of biological pathogens. This device operates by means of monitoring the change in transfer characteristics of the disk resonator when biological materials fall onto its active area. High sensitivity is achieved because the light wave interacts many times with each pathogen as a consequence of the resonant recirculation of light within the disk structure. Specificity of the detected substance can be achieved when a layer of antibodies or other binding material is deposited onto the active area of the resonator. Formulas are presented that allow the sensitivity of the device to be quantified and that show that, under optimum conditions, as few as 100 molecules can be detected.

© 2001 Optical Society of America

OCIS Codes
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(230.3990) Optical devices : Micro-optical devices

History
Original Manuscript: May 7, 2001
Revised Manuscript: August 1, 2001
Published: November 1, 2001

Citation
Robert W. Boyd and John E. Heebner, "Sensitive disk resonator photonic biosensor," Appl. Opt. 40, 5742-5747 (2001)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-40-31-5742


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