OSA's Digital Library

Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 40, Iss. 34 — Dec. 1, 2001
  • pp: 6381–6388

Acoustic modulation and photon–phonon scattering in optical coherence tomography

Paul A. Edney and Joseph T. Walsh, Jr.  »View Author Affiliations


Applied Optics, Vol. 40, Issue 34, pp. 6381-6388 (2001)
http://dx.doi.org/10.1364/AO.40.006381


View Full Text Article

Enhanced HTML    Acrobat PDF (431 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

Acousto-optic interactions allow the measurement of nonoptical material properties with high-resolution optical methods. We modulated a sample with ultrasound while simultaneously imaging with a traditional optical coherence tomography (OCT) system. The measured acousto-optic signal then depends on the mechanical response of the tissue to the applied modulation. The acquired acoustically enhanced OCT signals are consistent with established acousto-optic theory and provide enhanced contrast to OCT images.

© 2001 Optical Society of America

OCIS Codes
(070.1060) Fourier optics and signal processing : Acousto-optical signal processing
(170.0110) Medical optics and biotechnology : Imaging systems
(170.4090) Medical optics and biotechnology : Modulation techniques
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.5120) Medical optics and biotechnology : Photoacoustic imaging
(170.7170) Medical optics and biotechnology : Ultrasound

History
Original Manuscript: January 29, 2001
Revised Manuscript: August 21, 2001
Published: December 1, 2001

Citation
Paul A. Edney and Joseph T. Walsh, "Acoustic modulation and photon–phonon scattering in optical coherence tomography," Appl. Opt. 40, 6381-6388 (2001)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-40-34-6381


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, J. G. Fujimoto, “Optical coherence tomography,” Science 254, 1178–1181 (1991). [CrossRef] [PubMed]
  2. J. F. de Boer, T. E. Milner, J. C. van Gemert, J. S. Nelson, “Two-dimensional birefringence imaging in biological tissue by polarization-sensitive optical coherence tomography,” Opt. Lett. 22, 934–936 (1997). [CrossRef] [PubMed]
  3. X. J. Wang, T. E. Milner, Z. Chen, J. S. Nelson, “Measurement of fluid-flow-velocity profile in turbid media by the use of optical Doppler tomography,” Appl. Opt. 36, 144–149 (1997). [CrossRef] [PubMed]
  4. Z. Chen, T. E. Milner, S. Srinivas, X. Wang, A. Malekafzali, M. J. C. van Gemert, J. S. Nelson, “Noninvasive imaging of in vivo blood flow velocity using optical Doppler tomography,” Opt. Lett. 22, 1119–1121 (1997). [CrossRef] [PubMed]
  5. J. A. Izatt, M. D. Kulkarni, S. Yazdanfar, J. K. Barton, A. J. Welch, “In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomography,” Opt. Lett. 22, 1439–1441 (1997). [CrossRef]
  6. K. W. Ferrara, “Blood flow measurements using ultrasound,” in The Biomedical Engineering Handbook (CRC Press, Boca Raton, Fla., 1995).
  7. Y. Zhao, Z. Chen, C. Saxer, S. Xiang, J. F. de Boer, S. J. Nelson, “Phase-resolved optical coherence tomography and optical Doppler tomography for imaging blood flow in human skin with fast scanning speed and high velocity sensitivity,” Opt. Lett. 25, 114–116 (2000). [CrossRef]
  8. J. M. Schmitt, X. Bao, S. Xiao, “Micro-elastography of tissue with OCT,” in Coherence Domain Optical Methods in Biomedical Science and Clinical Applications II, V. V. Tuchon, J. A. Izatt, eds., Proc. SPIE3598, 47–55 (1999).
  9. C. Kittel, Introduction to Solid State Physics, 6th ed. (Wiley, New York, 1986).
  10. N. W. Ashcroft, N. D. Mermin, Solid State Physics (Saunders College, Philadelphia, Pa., 1976).
  11. A. Korpel, Acousto-Optics, 2nd ed. (Marcel Dekker, New York, 1997).
  12. R. D. Guenther, Modern Optics (Wiley, New York, 1990).
  13. J. M. Schmitt, “Optical coherence tomography (OCT): a review,” IEEE J. Sel. Top. Quantum. Electron. 5, 1205–1215 (1999). [CrossRef]
  14. M. E. Brezinksi, G. J. Tearney, N. J. Weissman, S. A. Boppart, B. E. Bouma, M. R. Hee, A. E. Weyman, E. A. Swanson, J. F. Southern, J. G. Fujimoto, “Assesing atherosclerotic plaque morphology: comparison of optical coherence tomography and high frequency intravascular ultrasound,” Heart 77, 397–403 (1997).
  15. C. J. Pavlin, M. D. Sherar, F. S. Foster, “Subsurface ultrasound microscopic imaging of the intact eye,” Ophthalmology 97, 244–250 (1990). [CrossRef] [PubMed]
  16. C. J. Pavlin, K. Harasiewicz, M. D. Sherar, F. S. Foster, “Clinical use of ultrasound biomicroscopy,” Ophthalmology 98, 287–295 (1990). [CrossRef]
  17. C. J. Pavlin, K. Harasiewicz, F. S. Foster, “Ultrasound biomicroscopy of anterior segment structures in normal and glaucomatous eyes,” Am. J. Ophthalmol. 113, 381–389 (1992). [PubMed]
  18. C. J. Pavlin, F. S. Foster, “Ultrasound biomicroscopy in glaucoma,” Acta Ophthalmol. Suppl. 204, 7–9 (1992). [PubMed]
  19. C. J. Pavlin, P. Macken, G. E. Trope, G. Heathcote, M. Sherar, K. Harasiewicz, F. S. Foster, “Ultrasound biomicroscopic imaging of the effects of YAG laser cycloablation in postmortem eyes and living patients,” Ophthalmology 102, 334–341 (1995). [CrossRef] [PubMed]
  20. C. J. Pavlin, “Practical application of ultrasound biomicroscopy,” Can. J. Ophthalmol. 30, 225–229 (1995). [PubMed]
  21. B. Bouma, G. J. Tearney, S. A. Boppart, M. R. Hee, M. E. Brezinski, J. G. Fujimoto, “High-resolution optical coherence tomographic imaging using a mode-locked Ti:Al2O3 laser source,” Opt. Lett. 20, 1486–1488 (1995). [CrossRef] [PubMed]
  22. M. D. Kulkarni, C. W. Thomas, J. A. Izatt, “Image enhancement in optical coherence tomography using deconvolution,” Electron. Lett. 33, 1365–1367 (1997). [CrossRef]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited