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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 41, Iss. 22 — Aug. 1, 2002
  • pp: 4603–4610

Design of a high-numerical-aperture miniature microscope objective for an endoscopic fiber confocal reflectance microscope

Chen Liang, Kung-Bin Sung, Rebecca R. Richards-Kortum, and Michael R. Descour  »View Author Affiliations


Applied Optics, Vol. 41, Issue 22, pp. 4603-4610 (2002)
http://dx.doi.org/10.1364/AO.41.004603


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Abstract

An endoscopic confocal microscope requires a high-performance, miniaturized microscope objective. We present the design of a miniature water-immersion microscope objective that is approximately 10 times smaller in length than a typical commercial objective. The miniature objective is 7 mm in outer diameter and 21 mm in length (from object to image). It is used in a fiber confocal reflectance microscope. The miniature microscope objective has a numerical aperture of 1.0, a field of view of 250 µm, and a working distance of 450 µm. It delivers diffraction-limited performance at λ = 1064 nm. Micro-meter-level resolution has been experimentally demonstrated.

© 2002 Optical Society of America

OCIS Codes
(110.0180) Imaging systems : Microscopy
(170.1790) Medical optics and biotechnology : Confocal microscopy
(220.3620) Optical design and fabrication : Lens system design

History
Original Manuscript: March 26, 2002
Published: August 1, 2002

Citation
Chen Liang, Kung-Bin Sung, Rebecca R. Richards-Kortum, and Michael R. Descour, "Design of a high-numerical-aperture miniature microscope objective for an endoscopic fiber confocal reflectance microscope," Appl. Opt. 41, 4603-4610 (2002)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-41-22-4603


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