Measurements of the contrast value of time-averaged speckle-modulated images of cartilage tissue are used to study tissue thermal modification in the case of laser-light treatment. This modification is related to thermally induced internal stress relaxation in the matrix of the treated tissue. The specific feature of the evolution of time-averaged speckle contrast with a change in the current temperature of modified collagen tissue is the typical looplike form of the contrast-temperature dependencies associated with irreversible changes in tissue structure and correlated with changes in the tissue diffuse transmittance and the tissue internal stress mentioned by other researchers.
© 2002 Optical Society of America
Dmitry A. Zimnyakov, Dmitry N. Agafonov, Alexander P. Sviridov, Alexander I. Omel’chenko, Liana V. Kuznetsova, and Victor N. Bagratashvili, "Speckle-Contrast Monitoring of Tissue Thermal Modification," Appl. Opt. 41, 5989-5996 (2002)