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Applied Optics

Applied Optics


  • Vol. 41, Iss. 31 — Nov. 1, 2002
  • pp: 6614–6620

Parallel flow measurements in microstructures by use of a multifocal 4 × 1 diffractive optical fan-out element

Hans Blom, Mathias Johansson, Michael Gösch, Toni Sigmundsson, Johan Holm, Sverker Hård, and Rudolf Rigler  »View Author Affiliations

Applied Optics, Vol. 41, Issue 31, pp. 6614-6620 (2002)

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We have developed a multifocal optical fluorescence correlation spectroscopy system for parallel flow analyses. Multifocal excitation was made possible through a 4 × 1 diffractive optical fan-out element, which produces uniform intensity in all four foci. Autocorrelation flow analyses inside a 20 µm × 20 µm square microchannel, with the 4 × 1 fan-out foci perpendicular to the flow direction, made it possible to monitor different flows in all four foci simultaneously. We were able to perform cross-correlation flow analyses by turning the microstructure, thereby having all four foci parallel to the direction of flow. Transport effects of the diffusion as a function of flow and distance could then also be studied.

© 2002 Optical Society of America

OCIS Codes
(050.1950) Diffraction and gratings : Diffraction gratings
(220.4000) Optical design and fabrication : Microstructure fabrication
(280.2490) Remote sensing and sensors : Flow diagnostics
(300.2530) Spectroscopy : Fluorescence, laser-induced

Original Manuscript: April 5, 2002
Revised Manuscript: July 22, 2002
Published: November 1, 2002

Hans Blom, Mathias Johansson, Michael Gösch, Toni Sigmundsson, Johan Holm, Sverker Hård, and Rudolf Rigler, "Parallel flow measurements in microstructures by use of a multifocal 4 × 1 diffractive optical fan-out element," Appl. Opt. 41, 6614-6620 (2002)

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