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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 41, Iss. 4 — Feb. 1, 2002
  • pp: 805–812

High-resolution full-field optical coherence tomography with a Linnik microscope

Arnaud Dubois, Laurent Vabre, Albert-Claude Boccara, and Emmanuel Beaurepaire  »View Author Affiliations


Applied Optics, Vol. 41, Issue 4, pp. 805-812 (2002)
http://dx.doi.org/10.1364/AO.41.000805


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Abstract

We describe an original microscope for high-resolution optical coherence tomography applications. Our system is based on a Linnik interference microscope with high-numerical-aperture objectives. Lock-in detection of the interference signal is achieved in parallel on a CCD by use of a photoelastic birefringence modulator and full-field stroboscopic illumination with an infrared LED. Transverse cross-section (en-face, or XY) images can be obtained in real time with better than 1-µm axial (Z) resolution and 0.5-µm transverse (XY) resolution. A sensitivity of ∼80 dB is reached at a 1-image/s acquisition rate, which allows tomography in scattering media such as biological tissues.

© 2002 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.6900) Medical optics and biotechnology : Three-dimensional microscopy
(180.3170) Microscopy : Interference microscopy

History
Original Manuscript: June 4, 2001
Revised Manuscript: September 24, 2001
Published: February 1, 2002

Citation
Arnaud Dubois, Laurent Vabre, Albert-Claude Boccara, and Emmanuel Beaurepaire, "High-resolution full-field optical coherence tomography with a Linnik microscope," Appl. Opt. 41, 805-812 (2002)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-41-4-805

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