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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 42, Iss. 16 — Jun. 1, 2003
  • pp: 3205–3214

Catheter for diagnosis and therapy with infrared evanescent waves

Brett A. Hooper, Anjul Maheshwari, Adam C. Curry, and Todd M. Alter  »View Author Affiliations


Applied Optics, Vol. 42, Issue 16, pp. 3205-3214 (2003)
http://dx.doi.org/10.1364/AO.42.003205


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Abstract

We have developed an optical delivery device (catheter) capable of transmitting broadband infrared light (IR wavelengths from 2 to 10 μm) for both diagnostic and therapeutic applications. The catheter is 1.68 mm in outer diameter and 1 m in length. It consists of two hollow glass waveguides coupled to a high-refractive-index optic tip. The IR light interacts with the tissue at the optic-tissue interface to measure the spectral signatures and perform therapy on the tissue at this interface. Fourier-transform IR spectrophotometer light is used to obtain the spectral signatures, and an IR free-electron laser (FEL) is used to study the therapeutic interaction of evanescent waves with the tissue. We present our catheter design; preliminary IR spectroscopy of aorta, blood, fatty tissue, and muscle; and IR FEL therapy on atherosclerotic aorta.

© 2003 Optical Society of America

OCIS Codes
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.1020) Medical optics and biotechnology : Ablation of tissue
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics
(230.7370) Optical devices : Waveguides
(240.6690) Optics at surfaces : Surface waves
(300.6340) Spectroscopy : Spectroscopy, infrared

History
Original Manuscript: August 30, 2002
Revised Manuscript: December 17, 2002
Published: June 1, 2003

Citation
Brett A. Hooper, Anjul Maheshwari, Adam C. Curry, and Todd M. Alter, "Catheter for diagnosis and therapy with infrared evanescent waves," Appl. Opt. 42, 3205-3214 (2003)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-42-16-3205


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