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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 42, Iss. 16 — Jun. 1, 2003
  • pp: 3313–3320

Streak camera: a multidetector for diffuse optical tomography

C. Virginie Zint, Wilfried Uhring, Murielle Torregrossa, Bernard Cunin, and Patrick Poulet  »View Author Affiliations


Applied Optics, Vol. 42, Issue 16, pp. 3313-3320 (2003)
http://dx.doi.org/10.1364/AO.42.003313


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Abstract

We describe an experimental setup for time-resolved diffuse optical tomography that uses a seven-channel light guide to transmit scattered light to a streak camera. This setup permits the simultaneous measurement of the time profiles of photons reemitted at different boundary sites of the objects studied. The instrument, its main specifications, and detector-specific data analysis before image reconstruction are described. The instrumentation was tested with phantoms simulating biological tissue, and the absorption and reduced scattering images that were obtained are discussed.

© 2003 Optical Society of America

OCIS Codes
(120.0120) Instrumentation, measurement, and metrology : Instrumentation, measurement, and metrology
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.0110) Medical optics and biotechnology : Imaging systems
(170.6920) Medical optics and biotechnology : Time-resolved imaging

History
Original Manuscript: August 29, 2002
Revised Manuscript: February 5, 2003
Published: June 1, 2003

Citation
C. Virginie Zint, Wilfried Uhring, Murielle Torregrossa, Bernard Cunin, and Patrick Poulet, "Streak camera: a multidetector for diffuse optical tomography," Appl. Opt. 42, 3313-3320 (2003)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-42-16-3313


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References

  1. J. C. Hebden, S. R. Arridge, D. T. Delpy, “Optical imaging in medicine. I. Experimental techniques,” Phys. Med. Biol. 42, 825–840 (1997). [CrossRef]
  2. J. C. Hebden, K. S. Wong, “Time-resolved optical tomography,” Appl. Opt. 32, 372–380 (1993). [CrossRef] [PubMed]
  3. D. A. Benaron, D. K. Stevenson, “Optical time of flight and absorbance imaging of biologic media,” Science 259, 1463–1466 (1993). [CrossRef] [PubMed]
  4. M. R. Hee, J. A. Izatt, J. M. Jacobson, J. G. Fujimoto, E. A. Swanson, “Femtosecond transillumination optical coherence tomography,” Opt. Lett. 18, 950–952 (1993). [CrossRef] [PubMed]
  5. D. T. Delpy, M. Cope, “Quantification in tissue near infrared spectroscopy,” Phil. Trans. R. Soc. London Ser. B 352, 649–659 (1997). [CrossRef]
  6. G. Mitic, J. Kölzer, J. Otto, E. Plies, G. Sölkner, W. Zinth, “Time-gated transillumination of biological tissues and tissuelike phantoms,” Appl. Opt. 33, 6699–6710 (1994). [CrossRef] [PubMed]
  7. F. E. W. Schmidt, “Development of a time-resolved optical tomography system for neonatal brain imaging,” Ph.D. dissertation (University College, London, 1999).
  8. F. E. W. Schmidt, M. E. Fry, E. M. C. Hillman, J. C. Hebden, D. T. Delpy, “A 32-channel time-resolved instrument for medical optical tomography,” Rev. Sci. Instrum. 71, 256–265 (2000). [CrossRef]
  9. V. Ntziachristos, X. Ma, B. Chance, “Time-correlated single photon counting imager for simultaneous magnetic resonance and near-infrared mammography,” Rev. Sci. Instrum. 69, 4221–4233 (1998). [CrossRef]
  10. H. Eda, I. Oda, Y. Ito, Y. Wada, Y. Oikawa, Y. Tsunazawa, M. Takada, Y. Tsuchiya, Y. Yamashita, M. Oda, A. Sassaroli, Y. Yamada, M. Tamura, “Multichannel time-resolved optical tomographic imaging system,” Rev. Sci. Instrum. 70, 3595–3602 (1999). [CrossRef]
  11. W. Uhring, C. V. Zint, P. Summ, Y. Hu, B. Cunin, “Very high long-term stability synchroscan streak camera,” Rev. Sci. Instrum. 74, 2646–2653 (2003). [CrossRef]
  12. A. Ishimaru, Wave Propagation and Scattering in Random Media (Academic, New York, 1978).
  13. S. R. Arridge, “Optical tomography in medical imaging,” Inverse Probl. 15, R41–R93 (1999). [CrossRef]
  14. S. R. Arridge, M. Schweiger, “Direct calculation of the moments of the distribution of photon time of flight in tissue with a finite-element method,” Appl. Opt. 34, 2683–2687 (1995). [CrossRef] [PubMed]
  15. C. V. Zint, F. Gao, M. Torregrossa, P. Poulet, “Near-infrared optical tomography of scattering cylindrical phantoms using time-resolved detection,” in Optical Tomography and Spectroscopy of Tissue IV, B. Chance, R. Alfano, B. Tromberg, M. Tamura, E. Sevick-Muraca, eds., Proc. SPIE4250, 514–521 (2001). [CrossRef]
  16. F. Gao, P. Poulet, Y. Yamada, “Simultaneous mapping of absorption and scattering coefficients from full three-dimensional model of time-resolved optical tomography,” Appl. Opt. 39, 5898–5910 (2000). [CrossRef]
  17. G. T. Herman, Image Reconstruction from Projections: The Fundamentals of Algorithm of Computerized Tomography (Academic, New York, 1980).
  18. M. Firbank, D. T. Delpy, “A design for a stable and reproducible phantom for use in near infra-red imaging and spectroscopy,” Phys. Med. Biol. 38, 847–853 (1993). [CrossRef]
  19. M. Schweiger, S. R. Arridge, “Application of temporal filters to time resolved data in optical tomography,” Phys. Med. Biol. 44, 1699–1717 (1999). [CrossRef] [PubMed]
  20. E. M. C. Hillman, J. C. Hebden, F. E. W. Schmidt, S. R. Arridge, M. S. Schweiger, H. Deghani, D. T. Delpy, “Calibration techniques and data types extraction for time-resolved optical tomography,” Rev. Sci. Instrum. 71, 3415–3427 (2000). [CrossRef]
  21. Hamamatsu Photonics KK, 314-5 Shimokanzo, Toyooka-mura, Iwata-gun, Shizuoka-ken, 438-0193 Japan (R4110U 8-anode MCP-PMT specifications, 2001).

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