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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 42, Iss. 25 — Sep. 1, 2003
  • pp: 5191–5197

Contrast Mechanisms in Polarization-Sensitive Mueller-Matrix Optical Coherence Tomography and Application in Burn Imaging

Shuliang Jiao, Wurong Yu, George Stoica, and Lihong V. Wang  »View Author Affiliations


Applied Optics, Vol. 42, Issue 25, pp. 5191-5197 (2003)
http://dx.doi.org/10.1364/AO.42.005191


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Abstract

We investigate the various contrast mechanisms provided by polarization-sensitive (PS) Mueller-matrix optical coherence tomography (OCT). Our PS multichannel Mueller-matrix OCT is the first, to our knowledge, to offer simultaneously comprehensive polarization-contrast mechanisms, including the amplitude of birefringence, the orientation of birefringence, and the diattenuation in addition to the polarization-independent intensity contrast, all of which can be extracted from the measured Jones or the equivalent Mueller matrix. Theoretical analysis shows that when diattenuation is negligible, the round-trip Jones matrix represents a linear retarder, which is the foundation of conventional PS-OCT, and can be calculated with a single incident polarization state, although the one-way Jones matrix generally represents an elliptical retarder; otherwise, two incident polarization states are needed. The experimental results obtained from rat skin samples, which conform well with the histology, show that Mueller OCT provides complementary structural and functional information on biological samples and reveal that polarization contrast is more sensitive to thermal degeneration of biological tissue than amplitude-based contrast. Thus, Mueller OCT has significant potential for application in the noninvasive assessment of burn depth.

© 2003 Optical Society of America

OCIS Codes
(120.2130) Instrumentation, measurement, and metrology : Ellipsometry and polarimetry
(170.1870) Medical optics and biotechnology : Dermatology
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(260.5430) Physical optics : Polarization

Citation
Shuliang Jiao, Wurong Yu, George Stoica, and Lihong V. Wang, "Contrast Mechanisms in Polarization-Sensitive Mueller-Matrix Optical Coherence Tomography and Application in Burn Imaging," Appl. Opt. 42, 5191-5197 (2003)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-42-25-5191


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References

  1. M. R. Hee, D. Huang, E. A. Swanson, and J. G. Fujimoto, “Polarization-sensitive low-coherence reflectometer for birefringence characterization and ranging,” J. Opt. Soc. Am. B 9, 903–908 (1992).
  2. J. F. de Boer, T. E. Milner, M. J. C. van Gemert, and J. S. Nelson, “Two-dimensional birefringence imaging in biological tissue by polarization-sensitive optical coherence tomography,” Opt. Lett. 22, 934–936 (1997).
  3. G. Yao and L.-H. V. Wang, “Two-dimensional depth-resolved Mueller matrix characterization of biological tissue by optical coherence tomography,” Opt. Lett. 24, 537–539 (1999).
  4. S. Jiao, G. Yao and L.-H. V. Wang, “Depth-resolved two-dimensional Stokes vectors of backscattered light and Mueller matrices of biological tissue measured with optical coherence tomography,” Appl. Opt. 39, 6318–6324 (2000).
  5. S. Jiao and L.-H. V. Wang, “Two-dimensional depth-resolved Mueller matrix of biological tissue measured with double-beam polarization-sensitive optical coherence tomography,” Opt. Lett. 27, 101–103 (2002).
  6. S. Jiao and L.-H. V. Wang, “Jones-matrix imaging of biological tissues with quadruple-channel optical coherence tomography,” J. Biomed. Opt. 7, 350–358 (2002).
  7. Z. Chen, T. E. Milner, D. Dave, and J. S. Nelson, “Optical Doppler tomography imaging of fluid flow velocity in highly scattering media,” Opt. Lett. 22, 64–66 (1997).
  8. J. A. Izatt, M. D. Kulkarni, S. Yazdanfar, J. K. Barton, and A. J. Welsh, “In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomography,” Opt. Lett. 22, 1439–1441 (1997).
  9. S. A. Boppart, M. E. Brezinski, C. Pitris, and J. G. Fujimoto, “Optical coherence tomography for neurosurgical imaging of human intracortical melanoma,” Neurosurgery 43, 1992–1998 (1998).
  10. B. H. Park, C. Saxer, S. M. Srinivas, J. S. Nelson, and J. F. de Boer, “In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography,” J. Biomed. Opt. 6, 474–479 (2001).
  11. G. Marquez, L.-H. Wang, S.-P. Lin, J. A. Schwartz, and S. L. Thomsen, “Anisotropy in the absorption and scattering spectra of chicken breast tissue,” Appl. Opt. 37, 798–804 (1998).
  12. C. Brosseau, Fundamentals of Polarized Light: A Statistical Optics Approach (Wiley, New York, 1998).
  13. S. Y. Lu and R. A. Chipman, “Homogenous and inhomogenous Jones matrix,” J. Opt. Soc. Am. A 11, 766–772 (1994).
  14. Y. Pan, R. Birngruber, J. Rosperich, and R. Engelhardt, “Low-coherence optical tomography in turbid tissue: theoretical analysis,” Appl. Opt. 34, 6564–6574 (1995).
  15. Y. Pan, R. Birngruber, and R. Engelhardt, “Contrast limits of coherence-gated imaging in scattering media,” Appl. Opt. 36, 2979–2983 (1997).
  16. S. Jiao, W. Yu, G. Stoica, and L.-H. V. Wang, “Optical-fiber-based Mueller optical coherence tomography,” Opt. Lett. 28, 1206–1208 (2003).
  17. J. M. Schmitt and S. H. Xiang, “Cross-polarized backscatter in optical coherence tomography of biological tissue,” Opt. Lett. 23, 1060–1062 (1998).
  18. M. I. Mishchenko and J. W. Hovenier, “Depolarization of light scattered by randomly oriented nonspherical particles,” Opt. Lett. 20, 1356–1358 (1995).

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