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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 43, Iss. 15 — May. 20, 2004
  • pp: 3048–3054

Measurement of the local optical properties of turbid media by differential path-length spectroscopy

Arjen Amelink and Henricus J. C. M. Sterenborg  »View Author Affiliations


Applied Optics, Vol. 43, Issue 15, pp. 3048-3054 (2004)
http://dx.doi.org/10.1364/AO.43.003048


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Abstract

We report on the development of an optical-fiber-based diagnostic tool with which to determine the local optical properties of a turbid medium. By using a single fiber in contact with the medium to deliver and detect white light, we have optimized the probability of detection of photons scattered from small depths. The contribution of scattered light from greater depths to the signal is measured and subtracted with an additional fiber, i.e., a collection fiber, to yield a differential backscatter signal. Phantoms demonstrate that, when photons have large mean free paths compared with the fiber diameter, single scattering dominates the differential backscatter signal. When photons have small mean free paths compared with the fiber diameter, the apparent path length of the photons that contribute to the differential backscatter signal becomes approximately equal to 4/5 of the fiber diameter. This effect is nearly independent of the optical properties of the sample under investigation.

© 2004 Optical Society of America

OCIS Codes
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics
(170.7050) Medical optics and biotechnology : Turbid media

History
Original Manuscript: October 1, 2003
Revised Manuscript: December 19, 2003
Published: May 20, 2004

Citation
Arjen Amelink and Henricus J. C. M. Sterenborg, "Measurement of the local optical properties of turbid media by differential path-length spectroscopy," Appl. Opt. 43, 3048-3054 (2004)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-43-15-3048

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