Abstract

Three-dimensional phosphorescence lifetime imaging is a novel method for the mapping of oxygen concentration in biological tissues. We present reconstruction techniques for recovering phosphorescent objects in highly scattering media based on the telegraph equation and two regularization methods, i.e., the Tikhonov—Phillips regularization and the maximum entropy method. Theoretical results are experimentally validated, and the reconstructed images of phosphorescent objects rendering oxygen maps in a layer are presented.

© 2004 Optical Society of America

Phosphorescence lifetime imaging in turbid media: the forward problem

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Tomographic imaging of oxygen by phosphorescence lifetime

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Dynamically adaptive mesh refinement technique for image reconstruction in optical tomography

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