OSA's Digital Library

Applied Optics

Applied Optics


  • Vol. 43, Iss. 32 — Nov. 10, 2004
  • pp: 6040–6046

Pulsed quantum-cascade laser-based sensor for trace-gas detection of carbonyl sulfide

Gerard Wysocki, Matt McCurdy, Stephen So, Damien Weidmann, Chad Roller, Robert F. Curl, and Frank K. Tittel  »View Author Affiliations

Applied Optics, Vol. 43, Issue 32, pp. 6040-6046 (2004)

View Full Text Article

Enhanced HTML    Acrobat PDF (428 KB)

Browse Journals / Lookup Meetings

Browse by Journal and Year


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools



Simultaneous exhaled carbonyl sulfide (OCS) and carbon dioxide concentration measurements in human breath are demonstrated with a compact pulsed quantum-cascade laser-based gas sensor. We achieved a noise-equivalent sensitivity (1σ) of 1.2 parts per billion by measuring a well-isolated OCS P(11) absorption line in the ν3 band at 2057.6 cm-1 using an astigmatic Herriott cell of 36-m optical path length and 0.4-s acquisition time.

© 2004 Optical Society of America

OCIS Codes
(280.3420) Remote sensing and sensors : Laser sensors
(300.1030) Spectroscopy : Absorption

Original Manuscript: March 19, 2004
Revised Manuscript: July 12, 2004
Published: November 10, 2004

Gerard Wysocki, Matt McCurdy, Stephen So, Damien Weidmann, Chad Roller, Robert F. Curl, and Frank K. Tittel, "Pulsed quantum-cascade laser-based sensor for trace-gas detection of carbonyl sulfide," Appl. Opt. 43, 6040-6046 (2004)

Sort:  Author  |  Year  |  Journal  |  Reset  


  1. M. Von Hobe, G. A. Cutter, A. J. Kettle, M. O. Andreae, “Dark production: a significant source of oceanic OCS,” J. Geophys. Res. 106C, 31217–31226 (2001). [CrossRef]
  2. A. J. Kettle, U. Kuhn, M. von Hobe, J. Kesselmeier, M. O. Andreae, “Global budget of atmospheric carbonyl sulfide: temporal and spatial variations of the dominant sources and sinks,” J. Geophys. Res. 107D, 25-1–25-16 (2002).
  3. P. D. N. Svoronos, T. J. Bruno, “Carbonyl sulfide: a review of its chemistry and properties,” Ind. Eng. Chem. Res. 41, 5321–5336 (2002). [CrossRef]
  4. S. M. Studer, J. B. Orens, I. Rosas, J. A. Krishnan, K. A. Cope, S. Yang, J. V. Conte, P. B. Becker, T. H. Risby, “Patterns and significance of exhaled-breath biomarkers in lung transplant recipients with acute allograft rejection,” J. Heart Lung Transplant 20, 1158–1166 (2001). [CrossRef] [PubMed]
  5. S. S. Sehnert, L. Jiang, J. F. Burdick, T. H. Risby, “Breath biomarkers for detection of human liver diseases: preliminary study,” Biomarkers 7, 174–187 (2002). [CrossRef] [PubMed]
  6. P. A. Steudler, W. Kijowski, “Determination of reduced sulfur gases in air by solid absorbent preconcentration and gas chromatography,” Anal. Chem. 56, 1432–1436 (1984). [CrossRef]
  7. W. Wardencki, “Problems with the determination of environmental sulphur compounds by gas chromatography,” J. Chromatog. A 793, 1–19 (1998). [CrossRef]
  8. Y. Inomata, K. Matsunaga, Y. Murai, K. Osada, Y. Iwasaka, “Simultaneous measurement of volatile sulfur compounds using ascorbic acid for oxidant removal and gas chromatography—flame photometric detection,” J. Chromatog. A 864, 111–119 (1999). [CrossRef]
  9. A. Fried, J. R. Drummond, B. Henry, J. Fox, “Versatile integrated tunable diode laser system for high precision: application for ambient measurements of OCS,” Appl. Opt. 30, 1916–1932 (1991). [CrossRef] [PubMed]
  10. A. A. Kosterev, F. K. Tittel, “Chemical sensors based on quantum cascade lasers,” IEEE J. Quantum Electron. 38, 582–591 (2002). [CrossRef]
  11. C. Roller, A. A. Kosterev, F. K. Tittel, K. Uehara, C. Gmachl, D. L. Sivco, “Carbonyl sulfide detection with a thermoelectrically cooled mid-infrared quantum cascade laser,” Opt. Lett. 28, 2052–2054 (2003). [CrossRef] [PubMed]
  12. K. Namjou, S. Cai, E. A. Whittaker, J. Faist, C. Gmachl, F. Capasso, D. L. Sivco, A. Y. Cho, “Sensitive absorption spectroscopy with a room-temperature distributed-feedback quantum-cascade laser,” Opt. Lett. 23, 219–221 (1998). [CrossRef]
  13. D. D. Nelson, J. H. Shorter, J. B. McManus, M. S. Zahniser, “Sub-part-per-billion detection of nitric oxide in air using a thermoelectrically cooled mid-infrared quantum cascade laser spectrometer,” Appl. Phys. B 75, 343–350 (2002). [CrossRef]
  14. D. Weidmann, A. A. Kosterev, C. Roller, R. F. Curl, M. P. Fraser, F. K. Tittel, “Monitoring of ethylene by a pulsed quantum cascade laser,” Appl. Opt. 43, 3329–3334 (2004). [CrossRef] [PubMed]
  15. H. C. Niu, D. A. Schoeller, P. D. Klein, “Improved gas chromatographic quantitation of breath hydrogen by normalization to respiratory carbon dioxide,” J. Lab. Clin. Med. 94, 755–763 (1979). [PubMed]
  16. C. Roller, K. Namjou, J. D. Jeffers, M. Camp, A. Mock, P. J. McCann, J. Grego, “Nitric oxide breath testing by tunable-diode laser absorption spectroscopy: application in monitoring respiratory inflammation,” Appl. Opt. 41, 6018–6029 (2002). [CrossRef] [PubMed]
  17. L. S. Rothman, A. Barbe, D. C. Benner, L. R. Brown, C. Camy-Peyret, M. R. Carleer, K. Chance, C. Clerbaux, V. Dana, V. M. Devi, A. Fayt, J.-M. Flaud, R. R. Gamache, A. Goldman, D. Jacquemart, K. W. Jucks, W. J. Lafferty, J.-Y. Mandin, S. T. Massie, V. Nemtchinov, D. A. Newnham, A. Perrin, C. P. Rinsland, J. Schroeder, K. M. Smith, M. A. H. Smith, K. Tang, R. A. Toth, J. Vander Auwera, P. Varanasi, K. Yoshino, “The HITRAN molecular spectroscopic database: edition of 2000 including updates through 2001,” J. Quant. Spectrosc. Radiat. Transfer 82, 5–44 (2003). [CrossRef]
  18. J. Faist, C. Gmachl, F. Capasso, C. Sirtori, D. L. Sivco, J. N. Baillargeon, A. Y. Cho, “Distributed feedback quantum cascade lasers,” Appl. Phys. Lett. 70, 2670–2672 (1997). [CrossRef]
  19. A. A. Kosterev, R. F. Curl, F. K. Tittel, R. Köhler, C. Gmachl, F. Capasso, D. L. Sivco, A. Y. Cho, “Transportable automated ammonia sensor based on a pulsed thermoelectrically cooled quantum-cascade distributed feedback laser,” Appl. Opt. 41, 573–578 (2002). [CrossRef] [PubMed]
  20. A. A. Kosterev, A. L. Malinovsky, F. K. Tittel, C. Gmachl, F. Capasso, D. L. Sivco, J. N. Baillargeon, A. L. Hutchinson, A. Y. Cho, “Cavity ringdown spectroscopic detection of nitric oxide with a continuous-wave quantum-cascade laser,” Appl. Opt. 40, 5522–5529 (2001). [CrossRef]
  21. K. A. Cope, M. T. Watson, M. Foster, S. S. Sehnert, T. H. Risby, “Effects of ventilation on the collection of exhaled breath in humans,” J. Appl. Physiol. 96, 1371–1379 (2004). [CrossRef]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited