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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 44, Iss. 10 — Apr. 1, 2005
  • pp: 1898–1904

Monitoring recovery after laser surgery of the breast with optical tomography: a case study

Jeremy C. Hebden, Tara D. Yates, Adam Gibson, Nicholas Everdell, Simon R. Arridge, Dennis W. Chicken, Michael Douek, and Mohammed R. S. Keshtgar  »View Author Affiliations


Applied Optics, Vol. 44, Issue 10, pp. 1898-1904 (2005)
http://dx.doi.org/10.1364/AO.44.001898


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Abstract

Results are presented of a study to monitor the changes in the optical properties of breast tissue over a 12-month period after interstitial laser photocoagulation treatment of a fibroadenoma. The study involved generating cross-sectional images of the breast with a multichannel time-resolved imaging system and a nonlinear image reconstruction algorithm. Images of the internal absorbing and scattering properties revealed the expected initial inflammatory response, followed by the development of low-scattering cysts consistent with corresponding ultrasound examinations. Although results indicate that purely qualitative images can potentially provide clinically valuable data, means of enhancing diagnostic information by overcoming present limitations of the approach are discussed.

© 2005 Optical Society of America

OCIS Codes
(170.1610) Medical optics and biotechnology : Clinical applications
(170.3830) Medical optics and biotechnology : Mammography
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.6920) Medical optics and biotechnology : Time-resolved imaging

Citation
Jeremy C. Hebden, Tara D. Yates, Adam Gibson, Nicholas Everdell, Simon R. Arridge, Dennis W. Chicken, Michael Douek, and Mohammed R. S. Keshtgar, "Monitoring recovery after laser surgery of the breast with optical tomography: a case study," Appl. Opt. 44, 1898-1904 (2005)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-44-10-1898


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References

  1. T. O. McBride, B. W. Pogue, J. Jiang, U. L. Österberg, and K. D. Paulsen, "A parallel-detection frequency-domain near-infrared tomography system for hemoglobin imaging of the breast in vivo," Rev. Sci. Instrumen.  72, 1817-1824 (2001).
  2. J. P. Culver, R. Choe, M. J. Holboke, L. Zubkov, T. Durduran, A. Slemp, V. Ntziachristos, B. Chance, and A. G. Yodh, "Three-dimensional diffuse optical tomography in the parallel plane transmission geometry: evaluation of a hybrid frequency domain/continuous wave clinical system for breast imaging," Med. Phys.  30, 235-247 (2003).
  3. R. L. Barbour, C. H. Schmitz, D. P. Klemer, Y. Pei, and H. L. Graber, "Design and initial testing of system for simultaneous dynamic optical tomographic mammography," in Proceedings of Biomedical Optics Topical Meetings (Optical Society of America, Washington, DC, 2004), WD4.
  4. D. Grosenick, K. T. Moesta, H. Wabnitz, J. Mucke, C. Stroszczynski, R. Macdonald, P. M. Schlag, and H. Rinneberg, "Time-domain optical mammography: initial clinical results on detection and characterization of breast tumors," Appl. Opt.  42, 3170-3186 (2003).
  5. P. Taroni, G. Danesini, A. Torricelli, A. Pifferi, L. Spinelli, and R. Cubeddu, "Clinical trial of time-resolved scanning optical mammography at 4 wavelengths between 683 and 975 nm," J. Biomed. Opt.  9, 464-473 (2004).
  6. Y. Xu, X. Gu, L. L. Fajardo, and H. Jiang, "In vivo breast imaging with diffuse optical tomography based on higher-order diffusion equations," Appl. Opt.  42, 3163-3169 (2003).
  7. A. Li, E. L. Miller, M. E. Kilmer, T. J. Brukilacchio, T. Chaves, J. Stott, Q. Zhang, T. Wu, M. Chorlton, R. H. Moore, D. B. Kopans, and D. A. Boas, "Tomographic optical breast imaging guided by three-dimensional mammography," Appl. Opt.  42, 5181-5190 (2003).
  8. V. E. Pera, E. L. Heffer, H. Siebold, O. Schütz, S. Heywang-Köbrunner, L. Götz, A. Heinig, and S. Fantini, "Spatial second-derivative image processing: an application to optical mammography to enhance the detection of breast tumors," J. Biomed. Opt.  8, 517-524 (2003).
  9. B. W. Pogue, S. Jiang, H. Dehghani, C. Kogel, S. Soho, S. Srinivasan, X. Song, T. D. Tosteson, S. P. Poplack, and P. D. Paulsen, "Characterization of hemoglobin, water, and NIR scattering in breast tissue: analysis of intersubject variability and menstrual cycle changes," J. Biomed. Opt.  9, 541-552 (2004).
  10. D. B. Jakubowki, A. E. Cerussi, F. Bevilacqua, N. Shah, D. Hsiang, J. Butler, and B. J. Tromberg, "Monitoring neoadjuvant chemotherapy in breast cancer using quantitative diffuse optical spectroscopy: a case study," J. Biomed. Opt.  9, 230-238 (2004).
  11. D. W. Chicken, A. C. Lee, G. M. Briggs, A. Mosse, M. A. Hall-Craggs, S. G. Bown, and M. R. S. Keshtgar, "Interstitial laser photocoagulation of fibroadenomas: a minimally invasive alternative to surgery," Brit. J. Surg.  91(S1), 121 (2004).
  12. J. C. Hebden and D. T. Delpy, "Diagnostic imaging with light," Brit. J. Radiol.  70, 206-214 (1997).
  13. F. E. W. Schmidt, M. E. Fry, E. M. C. Hillman, J. C. Hebden, and D. T. Delpy, "A 32-channel time-resolved instrument for medical optical tomography," Rev. Sci. Instrum.  71, 256-265 (2000).
  14. J. C. Hebden, A. Gibson, T. Austin, R. Md. Yusof, N. Everdell, D. T. Delpy, S. R. Arridge, J. H. Meek, and J. S. Wyatt, "Imaging changes in blood volume and oxygenation in the newborn infant brain using three-dimensional optical tomography," Phys. Med. Biol.  49, 1117-1130 (2004).
  15. S. R. Arridge and M. Schweiger, "Image reconstruction in optical tomography," Philos. Trans. R. Soc. London Ser. B  352, 717-726 (1997).
  16. M. Schweiger and S. R. Arridge, "Application of temporal filters to time resolved data in optical tomography," Phys. Med. Biol.  44, 1699-1717 (1999).
  17. J. C. Hebden, H. Veenstra, H. Dehghani, E. M. C. Hillman, M. Schweiger, S. R. Arridge, and D. T. Delpy, "Three-dimensional time-resolved optical tomography of a conical breast phantom," Appl. Opt.  40, 3278-3287 (2001).
  18. J. C. Hebden, T. Bland, E. M. C. Hillman, A. Gibson, N. Everdell, D. T. Delpy, S. R. Arridge, M. Douek, "Optical tomography of the breast using a 32-channel time-resolved imager," in Proceedings of Biomedical Optical Topical Meetings, OSA Technical Digest (Optical Society of America, Washington, DC, 2002), pp. 187-189.
  19. J. C. Hebden, F. M. Gonzalez, A. Gibson, E. M. C. Hillman, R. Yusof, N. Everdell, D. T. Delpy, G. Zaccanti, and F. Martelli, "Assessment of an in situ temporal calibration method for time-resolved optical tomography," J. Biomed. Opt.  8, 87-92 (2003).
  20. J. C. Hebden, A. Gibson, R. Md. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, "Three-dimensional optical tomography of the premature infant brain," Phys. Med. Biol.  47, 4155-4166 (2002).
  21. T. O. McBride, B. W. Pogue, S. Poplack, S. Soho, W. A. Wells, S. Jiang, U. L. Osterberg, and K. D. Paulsen, "Multispectral near-infrared tomography: a case study in compensating for water and lipid content in hemoglobin imaging of the breast," J. Biomed. Opt.  7, 72-79 (2002).
  22. A. Torricelli, L. Spinelli, A. Pifferi, P. Taroni, R. Cubeddu, and G. M. Danesini, "Use of a nonlinear perturbation approach for in vivo breast lesion characterization by multi-wavelength time-resolved optical mammography," Opt. Express  11, 853-967 (2003), http://www.opticsexpress.org.
  23. A. Y. Bluestone, G. Abdoulaev, C. H. Schmitz, R. L. Barbour, and A. H. Hielscher, "Three-dimensional optical tomography of hemodynamics in the human head," Opt. Express  9, 272-286 (2001), http://www.opticsexpress.org.
  24. S. B. Colak, D. G. Papaioannou, G. W. 't Hooft, M. B. van der Mark, H. Schomberg, J. C. J. Paasschens, J. B. M. Melissen, and N. van Asten, "Tomographic image reconstruction from optical projections in light-diffusing media," Appl. Opt.  36, 180-213 (1997).

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