A general framework for incorporating single and multiple priors in diffuse optical tomography is described. We explore the use of this framework for simultaneously utilizing spatial and spectral priors in the context of imaging breast cancer. The utilization of magnetic resonance images of water and lipid content as a statistical spatial prior for the diffuse optical image reconstructions is also discussed. Simulations are performed to demonstrate the significant improvement in image quality afforded by combining spatial and spectral priors.
© 2005 Optical Society of America
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5280) Medical optics and biotechnology : Photon migration
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics
(170.6960) Medical optics and biotechnology : Tomography
Ang Li, Greg Boverman, Yiheng Zhang, Dana Brooks, Eric L. Miller, Misha E. Kilmer, Quan Zhang, Elizabeth M. C. Hillman, and David A. Boas, "Optimal linear inverse solution with multiple priors in diffuse optical tomography," Appl. Opt. 44, 1948-1956 (2005)