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Applied Optics

Applied Optics

APPLICATIONS-CENTERED RESEARCH IN OPTICS

  • Vol. 44, Iss. 11 — Apr. 10, 2005
  • pp: 2094–2103

Practical and adequate approach to modeling light propagation in an adult head with low-scattering regions by use of diffusion theory

Tatsuya Koyama, Atsushi Iwasaki, Yosuke Ogoshi, and Eiji Okada  »View Author Affiliations


Applied Optics, Vol. 44, Issue 11, pp. 2094-2103 (2005)
http://dx.doi.org/10.1364/AO.44.002094


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Abstract

A practical and adequate approach to modeling light propagation in an adult head with a low-scattering cerebrospinal fluid (CSF) region by use of diffusion theory was investigated. The diffusion approximation does not hold in a nonscattering or low-scattering regions. The hybrid radiosity–diffusion method was adopted to model the light propagation in the head with a nonscattering region. In the hybrid method the geometry of the nonscattering region is acquired as a priori information. In reality, low-level scattering occurs in the CSF region and may reduce the error caused by the diffusion approximation. The partial optical path length and the spatial sensitivity profile calculated by the finite-element method agree well with those calculated by the Monte Carlo method in the case in which the transport scattering coefficient of the CSF layer is greater than 0.3 mm−1. Because it is feasible to assume that the transport scattering coefficient of a CSF layer is 0.3 mm−1, it is practical to adopt diffusion theory to the modeling of light propagation in an adult head as an alternative to the hybrid method.

© 2005 Optical Society of America

OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.3890) Medical optics and biotechnology : Medical optics instrumentation

History
Original Manuscript: July 20, 2004
Revised Manuscript: November 17, 2004
Manuscript Accepted: November 17, 2004
Published: April 10, 2005

Citation
Tatsuya Koyama, Atsushi Iwasaki, Yosuke Ogoshi, and Eiji Okada, "Practical and adequate approach to modeling light propagation in an adult head with low-scattering regions by use of diffusion theory," Appl. Opt. 44, 2094-2103 (2005)
http://www.opticsinfobase.org/ao/abstract.cfm?URI=ao-44-11-2094


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References

  1. I. Tachtsidis, C. E. Elwell, T. S. Leung, C.-W. Lee, M. Smith, D. T. Delpy, “Investigation of cerebral haemodynamics by near-infrared spectroscopy in young healthy volunteers reveals posture-dependent spontaneous oscillations,” Physiol. Meas. 25, 437–445 (2004). [CrossRef] [PubMed]
  2. G. Strangman, J. P. Culver, J. H. Thompson, D. A. Boas, “A quantitative comparison of simultaneous BOLD fMRI and NIRS recording during functional brain activation,” Neuroimage. 17, 719–731 (2002). [CrossRef] [PubMed]
  3. S. Kohri, Y. Hoshi, M. Tamura, C. Kato, Y. Kuge, N. Tamaki, “Quantitative evaluation of the relative contribution ratio of cerebral tissue to near-infrared signals in the adult human head: a preliminary study,” Physiol. Meas. 23, 301–312 (2002). [CrossRef] [PubMed]
  4. J. C. Hebden, A. Gibson, T. Austin, R. M. Yusof, N. Everdell, D. T. Delpy, S. R. Arridge, J. H. Meek, J. S. Wyatt, “Imaging changes in blood volume and oxygenation in the newborn infant brain using three-dimensional optical tomography,” Phys. Med. Biol. 49, 1117–1130 (2004). [CrossRef] [PubMed]
  5. B. Chance, E. Anday, S. Nioka, S. Zhou, L. Hong, K. Worden, C. Li, T. Murray, Y. Ovetsky, D. Pidikiti, R. Thomas, “A novel method for fast imaging of brain function, non-invasively, with light,” Opt. Express 2, 411–423 (1998), http://www.opticsexpress.org . [CrossRef] [PubMed]
  6. D. A. Boas, T. Gaudette, G. Strangman, X. Cheng, J. J. A. Marota, J. B. Mandeville, “The accuracy of near infrared spectroscopy and imaging during focal changes in cerebral hemodynamics,” Neuroimage. 13, 76–90 (2001). [CrossRef] [PubMed]
  7. H. Koizumi, T. Yamamoto, A. Maki, Y. Yamashita, H. Sato, H. Kawaguchi, N. Ichikawa, “Optical topography: practical problems and new applications,” Appl. Opt. 42, 3054–3062 (2003). [CrossRef] [PubMed]
  8. L. Wang, S. L. Jacques, L. Zheng, “MCML—Monte Carlo modeling of light transport in multi-layered tissue,” Comput. Methods Programs Biomed. 47, 131–146 (1995). [CrossRef] [PubMed]
  9. P. van der Zee, D. T. Delpy, “Simulation of the point spread function for light in tissue by a Monte Carlo technique,” Adv. Exp. Med. Biol. 215, 179–191 (1987). [CrossRef]
  10. M. Hiraoka, M. Firbank, M. Essenpreis, M. Cope, S. R. Arridge, P. van der Zee, D. T. Delpy, “A Monte Carlo investigation of optical pathlength in inhomogeneous tissue and its application to near-infrared spectroscopy,” Phys. Med. Biol. 38, 1859–1876 (1993). [CrossRef] [PubMed]
  11. S. R. Arridge, M. Schweiger, M. Hiraoka, D. T. Delpy, “A finite element approach for modeling photon transport in tissue,” Med. Phys. 20, 299–309 (1993). [CrossRef] [PubMed]
  12. W. Cui, L. E. Ostrander, “The relationship of surface reflectance measurements to optical properties of layered biological media,” IEEE Trans. Biomed. Eng. BME-39, 194–201 (1992). [CrossRef]
  13. A. H. Hielscher, A. D. Klose, K. M. Hanson, “Gradient-based iterative image reconstruction scheme for time-resolved optical tomography,” IEEE Trans. Med. Imaging 18, 262–271 (1999). [CrossRef] [PubMed]
  14. M. Firbank, S. R. Arridge, M. Schweiger, D. T. Delpy, “An investigation of light transport through scattering bodies with non-scattering regions,” Phys. Med. Biol. 41, 767–783 (1996). [CrossRef] [PubMed]
  15. E. Okada, M. Firbank, M. Schweiger, S. R. Arridge, M. Cope, D. T. Delpy, “Theoretical and experimental investigation of near-infrared light propagation in a model of the adult head,” Appl. Opt. 36, 21–31 (1997). [CrossRef] [PubMed]
  16. M. Firbank, E. Okada, D. T. Delpy, “A theoretical study of the signal contribution of regions of the adult head to near-infrared spectroscopy studies of visual evoked responses,” Neuroimage. 8, 69–78 (1998). [CrossRef] [PubMed]
  17. S. R. Arridge, H. Dehghani, M. Schweiger, E. Okada, “The finite element model for the propagation of light in scattering media: a direct method for domains with non-scattering regions,” Med. Phys. 27, 252–264 (2000). [CrossRef] [PubMed]
  18. H. Dehghani, D. T. Delpy, “Near-infrared spectroscopy of the adult head: effect of scattering and absorbing obstructions in the cerebrospinal fluid layer on light distribution in the tissue,” Appl. Opt. 39, 4721–4729 (2000). [CrossRef]
  19. H. Dehghani, S. R. Arridge, M. Schweiger, D. T. Delpy, “Optical tomography in the presence of void regions,” J. Opt. Soc. Am. A 17, 1659–1670 (2000). [CrossRef]
  20. S. R. Arridge, M. Schweiger, “Sensitivity to prior knowledge in optical tomographic reconstruction,” in Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation, B. Chance, R. R. Alfano, eds., Proc. SPIE2389, 378–388 (1995). [CrossRef]
  21. B. Pogue, K. D. Paulsen, “High-resolution near-infrared tomographic imaging simulations of the rat cranium by use of a priori magnetic resonance imaging structural information,” Opt. Lett. 23, 1716–1718 (1998). [CrossRef]
  22. A. H. Barnett, J. P. Culver, A. G. Sorensen, A. Dale, D. A. Boas, “Robust inference of baseline optical properties of the human head with three-dimensional segmentation from magnetic resonance imaging,” Appl. Opt. 42, 3095–3108 (2003). [CrossRef]
  23. E. Okada, D. T. Delpy, “Near-infrared light propagation in an adult head model. I. Modeling of low-level scattering in the cerebrospinal fluid layer,” Appl. Opt. 42, 2906–2914 (2003). [CrossRef] [PubMed]
  24. T. Hayashi, E. Okada, “Hybrid Monte Carlo–diffusion method for light propagation in tissue with a low scattering region,” Appl. Opt. 42, 2888–2896 (2003). [CrossRef] [PubMed]
  25. D. T. Delpy, M. Cope, P. van der Zee, S. R. Arridge, S. Wray, J. Wyatt, “Estimation of optical pathlength through tissue from direct time of flight measurement,” Phys. Med. Biol. 33, 1433–1442 (1988). [CrossRef] [PubMed]
  26. E. Okada, D. T. Delpy, “Near-infrared light propagation in an adult head model. II. Effect of superficial tissue thickness on the sensitivity of the near-infrared spectroscopy signal,” Appl. Opt. 42, 2915–2922 (2003). [CrossRef] [PubMed]
  27. C. R. Simpson, M. Kohl, M. Essenpreis, M. Cope, “Near-infrared optical properties of ex vivo human skin and subcutaneous tissues measured using the Monte Carlo inversion technique,” Phys. Med. Biol. 43, 2465–2478 (1998). [CrossRef] [PubMed]
  28. M. Firbank, M. Hiraoka, M. Essenpreis, D. T. Delpy, “Measurement of the optical properties of the skull in the wavelength range 650–950 nm,” Phys. Med. Biol. 38, 503–510 (1993). [CrossRef] [PubMed]
  29. P. van der Zee, M. Essenpreis, D. T. Delpy, “Optical properties of brain tissue,” in Photon Migration and Imaging in Random Media and Tissues, B. Chance, R. R. Alfano, eds., Proc. SPIE1888, 454–465 (1993). [CrossRef]
  30. S. R. Arridge, M. Schweiger, “Direct calculation of the moments of the distribution of photon time of flight in tissue with a finite-element method,” Appl. Opt. 34, 2683–2687 (1995). [CrossRef] [PubMed]
  31. M. Schweiger, S. R. Arridge, M. Hiraoka, D. T. Delpy, “The finite element method for the propagation of the light in scattering media: boundary and source conditions,” Med. Phys. 22, 1779–1792 (1995). [CrossRef] [PubMed]
  32. V. Tuchin, Tissue Optics: Light Scattering Methods and Instruments for Medical Diagnosis, D. C. O'Shea, ed. (SPIE, Bellingham, Wash., 2000).
  33. H. Dehghani, B. Brooksby, K. Bishwanath, B. W. Pogue, K. D. Paulsen, “The effects of internal refractive index variation in near-infrared optical tomography: a finite element modelling approach,” Phys. Med. Biol. 48, 2713–2727 (2003). [CrossRef] [PubMed]
  34. S. R. Arridge, M. Schweiger, “Photon-measurement density function. Part 2: Finite-element-method calculations,” Appl. Opt. 34, 8026–8037 (1995). [CrossRef] [PubMed]
  35. E. Okada, M. Schweiger, S. R. Arridge, M. Firbank, D. T. Delpy, “Experimental validation of Monte Carlo and finite-element methods for estimation of the optical path length in inhomogeneous tissue,” Appl. Opt. 35, 3362–3371 (1996). [CrossRef] [PubMed]
  36. S. T. Flock, M. S. Patterson, B. C. Wilson, D. R. Wyman, “Monte Carlo modeling of light propagation in highly scattering tissues—I: Model predictions and comparison with diffusion theory,” IEEE Trans. Biomed. Eng. 36, 1162–1168 (1989). [CrossRef] [PubMed]
  37. W. F. Chong, S. A. Prahl, A. J. Welch, “A review of the optical properties of biological tissue,” IEEE J. Quantum Electron. 26, 2166–2185 (1990). [CrossRef]

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